Navigation

0 Hits

  • Previous / Next

You are using Science Of Synthesis as a Guest.
Please login to access the full content or check if you have access via
1.4.4.2 (μ-Alkyne)hexacarbonyldicobalt(0) Complexes by Ligand Exchange

DOI: 10.1055/sos-SD-001-00322

Malacria, M.; Aubert, C.; Renaud, J.-L.Science of Synthesis, (20011487.

The reactions of alkynes with octacarbonyldicobalt(0) result in displacement of carbon monoxide and formation of zero-valent cobaltalkyne compounds. These complexes are useful in a great variety of reactions. Indeed, they are quite often used as the starting materials for the formation of cyclopentenones via the PausonKhand reaction.[‌208‌] They can efficiently stabilize propargyl cations[‌209‌] as well, and can serve as electrophilic propargyl synthons because of their reactivity towards a wide variety of heteroatom- and carbon-centered nucleophiles. This reaction, commonly referred to as the Nicholas reaction, has been reviewed[‌210‌,‌211‌] and successfully used for the synthesis of complex biologically active compounds.

Meeeee eeeeeeeee ee eeeeee eeeeeeeee eeee eeee eeeeeeee eeeeeeeee eeeeeeee eeee eeeeeeeeee eeeee eeeeeeeee, eeeeeeeee, eee eeeeeeeeee.[‌888‌] Mee eeeeeeeee ee eeeeeee eeeeeee [Me8(M8MMM8)(MM)8] eee eeeeeee eeeeeeee ee eeeeeeee eeeeeeeeeeeeeeeeeeee(8), eeeee ee eeeeeeeeeeee eeeeeeeee, eee eee eeeeee eeeeeeeee ee eeee eeeeeeeeeee ee e eeeeeeeeeee eeeeeee ee eeeeeeeeeeeeeee (Meeeee 88). Meeeeee eeee eeeeeee eee eeeeeeee eeeeeee eeeeeeee eeeeeee, eeeeeeeeeee eee eeeeeeeeeeeee eeeeeeeeeeeee eeeeeee, eeeeee, eeeeeee, eee eeeeee eeeeeee. Mee eeeeeeeee eee eeeeeeeee eeeeeeee ee eeeeeeeeeeeeee ee eeeeeee, eeeeee eee, ee Meeeeeee eee eee ee eeeeeeee ee 8888% eeeee. Meee eee eeeeeeee ee eee ee eeee eeeeee eeeeeee ee eeeeee eee eeee ee eeee eee eeeeeee eeeeeee ee eeeeeee eeeeeeee, eeeeee eeeeeeeeee eee-eeeeeeeee eeeeeeeee.

Meeeee 88 Meeeeeeee ee (μ-Meeeee)eeeeeeeeeeeeeeeeeeee(8) Meeeeeeee[‌888‌]

Meeeeeee eee eeeeeeee eeeeeee eeeeeeeeeeeeeeeeeeee(8) eee eee eeeeee eeeeeeeeee eee eeee eeeeeee eeeeeeeee ee eee eeeeeeeee, eeeeeee eeeeee eeeeeeeee eeeeeeeee eeeeeee eee eeeee eeeeeeeeeeeeee eeeeeeeee eee eeeee. Meeee eeeeeee eee eeeeeeeee ee eee eeeeeee eeee Me[Me(MM)8], MeMe[Me(MM)8], ee [Me8(MM)88].[‌888‌]

Me eee eeee eeeeeeeee eeee eee eeeeeeeee ee eee eeeeeeeee eeeee eeeeeee eeeeee ee eeeeee eeeeeeeeeeee eeeeeeeeeeee (MM8 eeeeeeeee)[‌888‌] ee ee e eeeeeeeee eeeeeeeee eeeee eeeeeeeeeeee ee eee [Me8(MM)8] (MM8 eeeeeeeee).[‌888‌]

Meeeeeeeeeee Meeeeeeee

(μ-Meeeee)eeeeeeeeeeeeeeeeeeee(8) Meeeeeeee 88; Meeeeee Meeeeeeee:[‌888‌]

Meeeeeeee eeee (Meeeeeee; Meee; Meeeeeee, Meeeeee Meeeeeeee), Meeeeeeee (8888), e888, eeee eeeeeeeeee eeee Meee Meeee eee Meee, Mee.

M 8-M, eee-eeeeee, eeeee-eeeeeeee eeeee eeeeee eeee e eeeeeeee eeeeeeee eee, eeeeeee, eee eee eeeee M-eeee eeeee eee eeeeeeee ee e eeeeeee eee eeeeeee, eee eeeee eeeee eeeee e eeee ee M8. Mee eeeee eee eeeeeee eeee eee MM8Me8 (888eM) eee eee eeeeee (8.888eee). Meeee eee eeeeeee eee eeeeeee eee 88eee, [Me8(MM)8] (88.8e, 8.888eee) eee eeeee ee eeeeeeee eeee e eee eeeeeee eeeee eeeeeeeeeee e eeee eeeeee ee M8. Meeeeeee eee eeeeeeeee (MMMMMMM: MM!) eee eeeeeeee. Mee eeeeeee eee eeeeeee eee 88e eee eee eeeeeee eee eeee eeeeeeeeeeee ee eeeee. Meeeee eeeeeeeeeeeeee (eeeeeee, eeeeee) eeeeeeee eee eeeeeeeeeeeee eeeeeee 88 ee e eeee eee eee ee eeeee.

References


Cookie-Einstellungen