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1.4.4.2 (μ-Alkyne)hexacarbonyldicobalt(0) Complexes by Ligand Exchange

DOI: 10.1055/sos-SD-001-00322

Malacria, M.; Aubert, C.; Renaud, J.-L.Science of Synthesis, (20011487.

The reactions of alkynes with octacarbonyldicobalt(0) result in displacement of carbon monoxide and formation of zero-valent cobaltalkyne compounds. These complexes are useful in a great variety of reactions. Indeed, they are quite often used as the starting materials for the formation of cyclopentenones via the PausonKhand reaction.[‌208‌] They can efficiently stabilize propargyl cations[‌209‌] as well, and can serve as electrophilic propargyl synthons because of their reactivity towards a wide variety of heteroatom- and carbon-centered nucleophiles. This reaction, commonly referred to as the Nicholas reaction, has been reviewed[‌210‌,‌211‌] and successfully used for the synthesis of complex biologically active compounds.

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