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Please login to access the full content or check if you have access via2.6.4.5 Method 5: Addition of Organochromium(III) Compounds to Carbonyl Compounds
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DOI:
10.1055/sos-SD-002-00315
Poli, R.; Smith, K. M., Science of Synthesis, (2003) 2, 310.
Under certain circumstances, organochromium(III) compounds transfer their alkyl or aryl groups to aldehydes and, less frequently, to ketones. The particular selectivity and tolerance of this reaction make it particularly useful in organic synthesis. The use of these chromium reagents may be advantageous for use with acid-sensitive substrates, because of their reduced Lewis acidity relative to other transfer reagents [e.g., trichloromethyltitanium(IV) or alkyltriisopropoxotitanium(IV)].
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