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Please login to access the full content or check if you have access via Method 1: Stoichiometric Reactions of Bis(η5-cyclopentadienyl)hydridozirconium(IV) and Bis(η5-cyclopentadienyl)dihydridozirconium(IV) Complexes and Related Reagents

DOI: 10.1055/sos-SD-002-00797

Negishi, E.-i.; Takahashi, T.Science of Synthesis, (20032712.

The synthetically most widely used and useful reaction of chlorobis(η5-cyclopentadienyl)hydridozirconium(IV) (53) and other related zirconium hydrides is hydrozirconation of alkenes and alkynes to produce the corresponding chlorobis(η5-cyclopentadienyl)monoorganozirconium complexes, where the monoorgano group is an alkyl or alkenyl group, respectively (Section Several extensive reviews on this topic have been reported.[‌18‌,‌91‌,‌92‌] Bis(η5-cyclopentadienyl)hydridozirconium derivatives also react with a wide variety of other functional groups. These reactions are important both as a means of reducing organic functional groups and for suppressing unwanted side reactions in the hydrozirconation of alkenes and alkynes (Section As stoichiometric reagents for organic synthesis, preformed and pure chlorobis(η5-cyclopentadienyl)hydridozirconi­um(IV) (53), in situ generated chlorobis(η5-cyclopentadienyl)hydridozirconium(IV) (53) and related reagents, and in situ generated chlorobis(η5-cyclopentadienyl)isobutylzirconium(IV) (57) have been most frequently used. However, other complexes, such as bis(η5-cyclopentadienyl)dihydridozirconium(IV) (52) and bis(η5-pentymethylcyclopentadienyl)dihydridozirconium(IV) (56),[‌93‌] may find a wide range of applications in the future.