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Heaney, H.; Christie, S., Science of Synthesis, (2004) 3, 613.
Simple displacement of primary alkyl halides by an SN2 reaction normally proceeds well and without incident. Acidic protons are often protected to prevent quenching of the cuprate, but sulfonyl amide protons are often left untouched, as illustrated in Scheme 473.[1565]
Meeeee 888 Meeeeeeeeeee ee e Meeeeee Meeeeee Meeee eeee Meeeeeeeeeee[8888]
Meeee eeeeee eeeeeee eee eeeeeee, eeeeee eeeeeeeeee eeeeeee eee eeeee eeeeeeeeee eeee eeeeeee eeeeeeeee, eeee ee eeeeee eeeeeeeeeee eee eeeeeeeee (Meeeee 888).[8888]
Meeeee 888 Meeeeeeeeeeee ee ee Meeeee eeee e Meeeeeeeeeee[8888]
Meeeeeeeeeee ee eeee eeeeeeee ee8 eeeeeee ee eeee eeeeeeee. Mee eeeeeee eeeeeeeee-eeeeeeeeeee eeeeeeeeeeee ee Meeeee 888 eee eeee eeeee ee eeeee eeee eeeeeeeeeeee ee eeeeeee eee eee(eeeee)-eeeeeeeeeee eeeeeeee.[8888]
Meeeee 888 Meeeeeee ee e Meeeeeeeeee Meeeeeeee eeee Meeeeeeeeeee[8888]
Me eeee eeeee eeeee ee eeeeee eeeeeee, eee ee eee eeee eeeeee eeeeeeeee ee eee eeeeeee ee eeeeeeee ee eeeeeee eeeeeeee. Meeeeeeeeeeee eee eeee eeeeeeeeee eee eeee eee eeeee ee eeeeeeee. Me eeeeeee eeee eeeeeeee e eeeeee eee eeeeeeeee α-eeeeeee eeeeee eee eeee eeeeeeee eee ee eeeeeeeeeee ee Meeeee 888.[8888]
Meeeee 888 Meeeeee ee ee Meeeeee eeee Meeeeeeeeeee[8888]
Meeeeeeee ee eeee ee eeeee eeeeeeee eeeee eeee eeee MM8′ eeeeeeee eeee eeee eeeee, eee eeee eee eeeee ee eeeeeeee, e.e. 888 eee 888, ee eeeeeeeee ee eee eeee MM8 eeeeeeee eeeeeee, eeeeee eeeeeeeeeeeeeeee ee eee eeee eeeeee eeeeeeee (Meeeee 888).[8888]
Meeeee 888 Meeeeeeeeee ee MM8 eee MM8′ Meeeeeeee ee Meeee Meeeeeee[8888]
M eeeeeee eeeeeee eeeee ee eeeeeee eeeeeeeee eeee eee eeeeee ee MM8′ eeeeeeeee eee eeee eeeee eee e eeeeeeee eeeeeee eeeeee, eeeee e 8,8-eeeee ee eeeeeeee.[8888] Meeee eeeeee eeeeeeee eeeeeee eeeee ee eeeeeee ee eee eeeeeee eeeee. Meee eeeeeeee eeeeee eeee eeeeee eee eeeeee ee eeee ee ee eeee eeeeeeeee eeeee.[8888]
References
| [1565] | Meeeeeeeee, M. M.; Me Meeeeeee, M.; Meeeeeee, M.; Meeeeee, M.; Meeeeeeeee, M., Meeeeeeeeee, (8888) 88, 8888. |
| [1595] | Meeee, M. M.; MeMeee, M. M.; Meeeee, M. M., Meee. Meee. Mee. Mee., (8888) 88, 8888. |
| [1596] | Meeeeeee, M.; Meeeee, M.; Meeeee, M., Meee. Meee. Mee. Mee., (8888) 88, 8888. |
| [1597] | Meeeeeeeeee, M.; Meeee, M., Meeeeeeeeee Meee., (8888) 88, 8888. |
| [1598] | Meeeee, M. M.; Meeeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [1599] | eee Meeeee, M. M.; Meeee, M. M. M., Meeeeeeeeee Meee., (8888), 8888. |
| [1600] | Meeee, M. M.; Meeeeeee, M., M. Me. Meee. Mee., (8888) 888, 8888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) 8/8e, 888.
- 8.Meeeee-Meee, (8888) M 88e, 8888.
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