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DOI:
10.1055/sos-SD-004-00909
Sarkar, T. K., Science of Synthesis, (2002) 4, 905.
Homoallylic alcohols are available by the reactions of allylsilanes with aldehydes or ketones either by prior activation of the carbonyl functionality with a Lewis acid or by prior activation of allylsilane itself with a Lewis base. In some exceptional cases,[42,43] no external activation is required; for an illustrative example see Scheme 5. Use of chiral Lewis acids[280] or chiral Lewis bases[281,282] allows asymmetric synthesis of homoallylic alcohols.
References
| [42] | Meeee, M.-M.; Meeeeee, M.; Meee, M., Meee. Meee., (8888), 888. |
| [43] | Meeeeeeee, M.; Meeeee, M.; Meeeeee, M., M. Mee. Meee., (8888) 88, 8888. |
| [280] | Meeee, M. M.; Meeeeeeeee, M.; Meeee-Meeeee, M., Meee. Meee. Meee., (8888) 888, 888. |
| [281] | Meeeeee, M. M.; Mee, M. M.; Meeee, M. M.; Meeeeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [282] | Meeeeeee, M.; Meeee, M.; Meeee, M.; Meeeeeeee, M.-e., M. Me. Meee. Mee., (8888) 888, 8888. |
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