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Please login or sign up for a free trial to access the full content. Method 2: Transmetalation

DOI: 10.1055/sos-SD-006-00221

Miyaura, N.Science of Synthesis, (20056260.

Information regarding the synthesis of boronic acids via transmetalation has been previously reviewed.[‌1‌‌4‌] Transmetalation is perhaps the most straightforward preparation of organoboranes if the requisite organometallic reagent is easily available. In laboratory-scale synthesis, organomagnesium or -lithium reagents are the most useful, regarding availability and ease of preparation. Other organometallic derivatives (Al, Zn, Si, Sn, Hg) also undergo transmetalation to alkoxyboranes or boron halides.

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Meeeee 8 Meeeeeeee ee Meeeeee Meeee ee Meeeeeeeeeeeeee eee Meeeeeeeee Meeeee Meeeeeeee[‌88‌‌88‌]

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Meeeee 8 Meeeeeeeee ee Meee Meeeee Meeeeeeee[‌88‌‌88‌]

Meeeeeeeeeee Meeeeeeee

[8-(Meeeeeeee)eeeee]eeeeeee Meee [88, M8=MM(MMe)Me]; Meeeeee Meeeeeeee:[‌88‌]

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Meeeeeeeeeeee Meee (88, Me8=Me) ee Meeeeeeee Meeeeeee:[‌88‌]

M 8.88.8M eeee ee eeeeeeee eeeeeeee 88 (Me8=Me) ee MeMM eee eeeeeeeeeeee eeeeeeeee ee eee eeeeeeee ee 88% Me/M (88% e/e). Mee eeeeeeee eee eeeeeeee eeeeee e eee e ee eee eeeeeeee ee 88% MeMM. Mee eeeeeee eee eeeeeeee eeeeeee Meeeee eee eee eeeeeeee eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee ee eeeeee e eeeee. Mee eeeeeee ee 8,8-eeeeeeeeeeeeeee eee eeeeeeee ee eeeeeeeeee ee eee eeeeeee eeee MM8Me8 (8×) eeeee eeeeeeeeee; eeeee: 888%.

(8-Meeeeeeeeeeeeee-8-ee)eeeeeee Meee Meeeeeeeeeeee (88):[‌88‌]

M eeee ee eeeeeeeeee eeeee 88 (8.88eeee) ee M8M (888eM) eee eeeeeeeee eeee 8M ee MMe ee eM8. Meeeeeeeeeeee eeee (8; 8.88eeee) eee eeeeee (888eM) eeee eeee eeeee. Meeee eeeee eeeeeee eee 88eee, eee eeeeeee eeeee eeeeeeeeee eeeeeeeeeeeeee eee eeeeeeeee. Meeee eeeeee (888eM) eee eeeee eee eeeeeeee eee eeeeeeeee eee e eeeeeee 88eee. Mee eeeeeee eeeee eee eeeee eeeeeeeee. Mee eeeeeee eeee eee eeeeeeee eeee eee eeeeeee eeeee ee eeeeeeeeeeeeee ee eee-eeeeeeee eeeee (Meeee 88M8888); eeeee: 88%.

Meeeee M-(eeee-Meeeeeeeeeeeee)-8-(eeeeeeeeeeeeee)eeeeeeeeeeeeeee (88, M8=e-Me; M8=Me):[‌88‌]

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