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Please login or sign up for a free trial to access the full content.7.6.11.7.2 Variation 2: Alkylmagnesium Bromide with Catalytic Titanium(IV) Isopropoxide
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Takahashi, T.; Liu, Y., Science of Synthesis, (2004) 7, 607.
As long as a titanacyclopropane can be formed, other alkyl Grignard reagents can be used instead of ethylmagnesium bromide. For example, when alkylmagnesium bromide [R1(CH2)2MgBr] is used as a Grignard reagent, the substituted titanacyclopropane 31 is formed in situ. In the cyclopropanol formation, the R1 group is incorporated into the product 32 as a substituent at C2 after hydrolysis of the reaction mixture (Scheme 21).[92,98,99]
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References
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| [98] | Meeee, M. M.; Mee, M. M.; Mee, M. M., M. Me. Meee. Mee., (8888) 888, 8888. |
| [99] | Mee, M.; Mee, M. M.; Mee, M. M., M. Me. Meee. Mee., (8888) 888, 8888. |
| [100] | Meeeee, M.; Meeeeeee, M.; Meeeeeeeeee, M.; Meeeee, M.; ee Meeeeee, M., Meeeeee, (8888), 8888. |
| [101] | Meeeeeeeee, M.; Meeeee, M.; Meeeee, M.; ee Meeeeee, M., Meeeeee, (8888), 888. |
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