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7.6.14.8 Method 8: Reactions Involving Magnesium Bis(dialkylamides)

DOI: 10.1055/sos-SD-007-00649

Shimizu, M.Science of Synthesis, (20047666.

(Dialkylamino)magnesium hydrides are prepared by treatment of magnesium bis(dialkyl­amide) compounds with an active form of magnesium hydride in an equimolar ratio in tetrahydrofuran. The reaction of (dialkylamino)magnesium hydrides with ketones gives the corresponding alcohols in good yields. Unsolvated magnesium bis(dialkylamide) compounds react smoothly with carboxylic acids to give the corresponding carboxamides 12 directly in good to excellent yields (Scheme 7).[‌10‌]

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