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9.9.1.3.1.2.5 Method 5: Base-Assisted Cyclization of 1-(4-Hydroxyalk-2-ynyl)benzotriazoles

DOI: 10.1055/sos-SD-009-00244

König, B.Science of Synthesis, (20019216.

Base-assisted cyclization of 1-(4-hydroxyalk-2-ynyl)benzotriazoles 159, derived from lithiated 1-(prop-2-ynyl)-1H-1,2,3-benzotriazole (158) and aromatic aldehydes or ketones, give 2-arylfurans 160 or 1-(5,5-diaryl-2,5-dihydro-2-furyl)benzotriazoles 161, respectively, in high yields (Scheme 54).[‌275‌,‌276‌]

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