Navigation

0 Hits

  • Previous / Next

You are using Science Of Synthesis as a Guest. Please login or sign up for a free trial to access the full content.
11.12.1.1.2.7 Method 7: From C,N-Diacylimines and Nitriles

DOI: 10.1055/sos-SD-011-00557

Boyd, G. V.Science of Synthesis, (200211397.

C,N-Diacylimine 54, generated by the action of Lewis acids on the amide 53, reacts in situ with nitriles in a complex process to yield mixtures of 4-(acylamino)oxazoles 55 and 56 (Scheme 23.)[‌54‌]

Meeeee 88 8-(Meeeeeeee)eeeeeeee eeee e M,M-Meeeeeeeeee eee Meeeeeee[‌88‌]

Meeeeeeeeee 88

M8 Meee (e) Meeee (%) ee 88 Meeee (%) ee 88 Mee
Me 8.8 88 88 [‌88‌]
MM=MMMe 8.8 88 88 [‌88‌]
Me 8 88e [‌88‌]
Me 8 88e [‌88‌]

e Meeee (%) ee 88+88. Meeee (88/88) 8.8:8.

e 88=88.

Meeeeeeeeeee Meeeeeeee

8-(Meeeeeeee)eeeeeeee 88 eee 88; Meeeeee Meeeeeeee:[‌88‌]

M eee eeee ee eee eeeeeeeeeee eeeeeeeee 88 (8.8eeee) ee e eeeeeee (M8MM; 8eM, eeeee eeeeee) eee eeeeeee eeee e eee. eeeeee ee MMMe8 ee MM8MMe8 (8.88eeee) ee 8888°M, eee eee eeeeeee eee eeeeeeeeee ee eeee eeeeeeeeeee eee 88e. Me eee eeee eeeeee eeee eee eeeee, M8MM8 eee eeeee eeeee eM 888 eee eeeeeee, eee eeeeeee eee eeeeeeeee eeee MMMe8, eee eeee eee eeeee, eee eeeeeee eee eeeeeee eeeee eeeeeee eeeeeeee, eee eee eeeeeee eee eeeeeeeeeeeeeee (eeeeee eee, MeMMe/eeeeee).

References