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Please login to access the full content or check if you have access via Method 5: From α-(Hydroxyamino)phenylacetic Acid and Aldehydes

DOI: 10.1055/sos-SD-011-00557

Boyd, G. V.Science of Synthesis, (200211408.

α-(Hydroxyamino)phenylacetic acid (101) condenses with aldehydes to give 2-substituted oxazol-5(4H)-ones 102 (Scheme 42).[‌111‌] The reaction with ketones yields 2,2-disubstituted 4-phenyloxazol-5(2H)-ones, a type of compound that is outside the scope of this section.

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