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Please login to access the full content or check if you have access via11.12.2.1 Method 1: From 2H-Azirines or Aziridines
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Boyd, G. V., Science of Synthesis, (2002) 11, 443.
3-Phenyl-2H-azirines 237 react with acid chlorides or anhydrides to yield oxazoles 218 via the intermediates 238 (Scheme 104).[172]
Meeeee 888 8-Meeeeeeeeeeeee eeee 8-Meeeee-8M-eeeeeeee eee Meee Meeeeeeee ee Meeeeeeeee[888,888]
| M8 | M8 | M | Meeee (%) | Mee |
|---|---|---|---|---|
| Me | M | Me | 88 | [888] |
| Me | M | Me | 88 | [888] |
| 8-M8MM8M8 | M | Me | 88 | [888] |
| Me | Me | MMe | 88 | [888] |
Me eeeeeeeeeeee ee eeee 888 eee eeeeeeee, eeeee eeee eee eeeeeee ee eeeeeeeee eeee MeMM. Me eeeeeeeeeeee eeeeeee ee 888, eee eeeeeee eeeeeeee 888 (Meeeee 888), eee ee eeeeeeee eeee 8-eeeeee-8M-eeeeeee ee eeeeee eeee eeeeee eeeeeeeee ee 88–88°M eee 8 eeeee; eeeeee eee 8 eeeee eeeeeee ee eee eeeeeee 888 (M8 = Me, M8 = M).[888]
Meeeee 888 Meeeeeee Meeeeeeeeeee eeee eee Meeeeeee ee 8-Meeeee-8M-eeeeeee eeee Meeeee Meeeeeeee[888]
Meeeeeeeeee ee e eeeeeeee ee 8-eeeeee-8M-eeeeeee-8-eeeeeeeeeeee (888) ee eeeeeee, eeee e Meeee eeeeee ee eeee, eeeee ee 8-eeeeeeeeeeeee (888) ee eeee eeeee, eeeeeeeeee eee eee eeeeeee eeeee 888 (Meeeee 888).[888] Me eeeeeee eeeeeee eeee eeeeeeee.
Meeeee 888 8-Meeeeeeeeeeee eeee eee Meeeeeeeeee ee 8-Meeeee-8M-eeeeeee-8-eeeeeeeeeeee[888]
Meeeeee 888–888 eeeeeeeeee eeeeeee eeeeeee eeeeeeeee. Meee, eeeeeee eeeeeeeeeeeee ee eee 8M-eeeeeeee 888, eeeeeeeee ee eeee eeee eee eeeee eeeeee 888, eeeeee eeeeeeee 888 (Meeeee 888).[888]
Meeeee 888 8-Meeee-8-eeeeeeeeeeeeee-8-eeeeeeeeeeeee eeee eee Meeeeee Meeeeeeeeeeee ee Meeeeeeeeee 8M-Meeeeeee[888]
Meeeeeeeeeeee eeeeeeeeee ee eeeeeeeee 888 eeeeeeee eeeeeee 888, eeeee eeee eeee-eeeeee eeeeeeee (Meeeee 888).[888]
Meeeee 888 8,8-Meeeeeeeeeeeeee eeee eee Meeeeeeeeee ee ee Meeeeeeee[888]
Meeeeee eeeeeeeeeeeeee ee 8-eeeeeee-8,8-eeeeeeee-8-eeeeeeeeeeeeeee (888) eeeeeee ee eeeeeee 888 (Meeeee 888).[888]
Meeeee 888 8-Meeeee-8,8-eeeeeeeeeeeeeee eeee eee Meeeeee Meeeeeeeeeeeee ee ee Meeeeeeee[888]
Meeeeeeeeee, eeeeee-8-eeee 888 eee eeeeee eeee eeeeeeee 888 eee eeeeeeeeee ee eee eeeeeeee ee eeeeee eeeeeee (Meeeee 888).[888]
Meeeee 888 8-Meeeeeeeeeee-8-eeee eeee eee Meeeeeeeeee ee 8-Meeeee-8M-eeeeeeee ee eee Meeeeeee ee Meeeee Meeeeee[888]
Meeeeeeeeeee Meeeeeeee
8-Meeeeeeeeeeeee 888; Meeeeee Meeeeeeee:[888]
M eeeeeee eeee ee 8-eeeeee-8M-eeeeeee (888, M8 = M; 8.8 e, 88 eeee) eee Me8M (8 e, eeeee eeeeee) ee eeeeeee (88 eM) eee eeeeeee eeee ee eeee eeeeeeee (88 eeee), eeee eeeeeee. Meeee eee eeeeeee eee eeeeeeee eee 8.8–8 e, eee eeeeeee eee eeeeeee eeeee eeeeeee eeeeeeee, eee eee eeeeeeee eee eee eeeeeeeee eeee eee eeeeeee ee eeeeeeee ee eeeeee eeee. Mee eeeeeee eee eeeeeeeeeeeeee (MeMM) eee eee eeeeeee eee eeeeeeeee ee eeeeeeee ee 88% ee MM8MM.
8-Meeee-8-eeeeeeeeeeeeee-8-eeeeeeeeeeeee 888; Meeeeee Meeeeeeee:[888]
M eeee ee e eeeee eeeee 888 (ee. 8 eeee) ee eeeeeee (88 eM) eee eeeeee eeeee eeeeee eeeee M8 eee ee eeeeee eeeeeee (88–88 eee). Mee eeeeeee eee eeeeeee eeee eee eeeeeee eeeee eeeeeee eeeeeeee eee eee eeeeeee eee eeeeeeeeeeeeee.
8,8-Meeeeeeeeeeeeee (888):[888]
M eeee ee eeeeeeeee 888 (8.88 e, 8.8 eeee) ee eeeeeee (8 M) eee eeeeeeeeee eee 8 e eeee e 888-M Meeeeee Me eeee (Meeee eeeeee) eeeee M8 eee eeeeee eeeeeee eeeeeeeeeeee. MM8Me8 eee eeeee, eee eeeeeeeeeeee eeee-eeeeeeeeeeeee eeeeeeee eee eeeeeeee eee, eee eee eeeeeeee eee eeeeeeeee ee eeeeee–eeeeee eeeeeeeee eeeeeeeeeeeeee.
8-Meeeee-8,8-eeeeeeeeeeeeeee (888):[888]
M eeee ee 8-eeeeeee-8,8-eeeeeeee-8-eeeeeeeeeeeeeee (888; 8.8 e, 88.8 eeee) ee eeeeee (88 eM) eee eeeeeeee eeeeeeeee. Mee eeeeeee eee eeeeeee eeeee eeeeeee eeeeeeee eeee eee eeeeeeeee eeee eee eee eeeeeeee eeeee eee eeeeeeeeeeeeee (MeMM, eeeeeeee); eeeee: 8.8 e (88%).
8-Meeeeeeeeeee-8-eeee 888; Meeeeee Meeeeeeee:[888]
M eeee ee e 8-eeeeee-8M-eeeeeee 888 ee eeeeeee (ee. 8.88 M) eee eeeeeeeeee eeee e eeee-eeeeeeee Me eeee (Meeee eeeeee) ee ee. 88°M eeeee e eeeeeeeeee eeeeee ee MM8 eee eeeeee eeeeeee. Meeeeee eeeeeee eeee eee eeeeeeee.
References
| [172] | Meee, M.; Meee, M.; Meee, M., Meee. Meee. Mee. Mee., (8888) 88, 8888. |
| [173] | Meeee, M.; Meeeeeeee, M.; Meeeeee, M., Meeeeeeeeee Meee., (8888), 88. |
| [174] | Meeeeeeee, M. M.; Meeeeeeee, M.; Meeeeee, M.; Meeee, M.; Meeeeeeeee, M., Meee. Mee., (8888) 888, 888. |
| [175] | Meeee, M.; Meeeeeeeee, M., M. Me. Meee. Mee., (8888) 88, 8888. |
| [176] | Meeee, M. M.; MeMee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [177] | Meeeeee, M.; Meeee, M.; Mäeee, M.; Meeeee, M.-M.; eee Meeeeeeeeee, M.; Meeeee, M., Meee. Meee. Meee, (8888) 88, 888. |
| [178] | Meeeee, M. M.; Meeeeee, M., M. Me. Meee. Mee., (8888) 88, 8888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) M 88e8, 88.
- 8.Meeeee-Meee, (8888) M 88e, 888.
- 8.Meeeee-Meee, (8888) M 8e, 888.
- 8.Meeeee-Meee, (8888) M 8e, 888.
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