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Please login to access the full content or check if you have access via11.17.1.4.2.2.1 Variation 1: From α-Functionalized Carboxylic Acid Derivatives and Aminothiocarbonyl Compounds
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Kikelj, D.; Urleb, U., Science of Synthesis, (2002) 11, 643.
α-Functionalized carboxylic acid derivatives 58 and aminothiocarbonyl compounds 56 yield thiazol-4(5H)-ones 59 (thiazol-4-ols 60) (Scheme 20).[91,188,190,194–196]
Meeeee 88 Meeeeeeee ee Meeeeee-8(8M)-eeee eeee α-Meeeeeeeeeeeee Meee Meeeeeeeeee eee Meeeeeeeeeeeeeeee Meeeeeeee[88,888,888,888–888]
| M8 | M8 | M | M | Meeeeeeeee | Meeee (%) | ee (°M) | Mee |
|---|---|---|---|---|---|---|---|
| MMM8/MMe | 8M-eeeee-8-eeeeeeee | MMe | MMe | MeMM, 88°M, 88 e | 88 | 888–888 | [888] |
| MM8 | M | MM(M)(MMe)8 | MMe | 888–888°M, 8 eee | 88 | 888–888 | [888] |
| MM8 | M | Me | MMMM8Me | eeeeeee, eeeeee, 8.8 e | 88 | 888 (eee) | [888] |
| MeMM | M | Me | MM | MeMMe/M8M, eeeeee, 88 eee | 88 | 888–888 | [888] |
| Me | M | Me | MMe | 888°M, 8 eee | 88 | 888–888 | [888] |
| Me | Me | Me | MMe | eeeeeeee/eeeeeee, 88°M, 8 e | 88 | 888–888 | [88] |
e Meeeeeee eeeeeeee/eeeeeee.
e Mee eeeeeee ee ee eee eee eeeeeeeeee eeee; ee eeeeeee eeeeeeeeeee.
Meeeeeeee ee M-eeeeeeeeeeeeeee eeeeeeeee 88 (M8 = MM8) eee α-eeeeeeee eeeeeee 88 ee eee eeeeeeee ee eeeeeeeeeeeee eeeeeee e eeeeeee eeeeeeeee ee eeeeeeeee eeeeeee-8-eee-8-eeeeee 88 (eeeeeeeeüeeeeeeee) (Meeeee 88).[888–888] Mee eeeeee eee eeee eee M,M,M′-eeeeeeeeeeeeee eeeeeeeee ee eeeeeeee eeeeeeeee.[888] Meeeeeeee ee 8-eeeeeeeeeee 8-eeeeeeeeeeeeeeeeeeeeee eeee eeeee eeeeeeeeeeee eeeeeeeee eeee M-eeeeeee eeeeeee-8-eee-8-eeeeee.[888]
Meeeee 88 Meeeeeeee ee Meeeeeeeüeeeeeeee (Meeeeee-8-eee-8-eeeeee) eeee α-Meeeeeee Meeeeee eee Meeeeeeeeee Meeeeeeee[888–888]
| M8 | M8 | M8 | M | Meeeeee | Meee, Meee | Meeee (%) | ee (°M) | Mee |
|---|---|---|---|---|---|---|---|---|
| MMe8 | Me | Me | Me | eee MMMe8 | ee, 8 eee | 88 | 888 (eee) | [888] |
| MMeMe | Me | Me | MM | eeeeeee | ee, 88 e | 88 | 888–888 (eee) | [888] |
| MMe | Me | Me | MM | Me8M, eeeeeee | 88°M, 88 e | 88 | 888–888 (eee) | [888] |
Meeeeeeeeeee Meeeeeeee
8-Meeeee-8-eeeeeeeeeeeee-8(8M)-eee (88, M8 = Me; M8 = Me):[88]
Meeee 8-eeeeeeeeeeeeeee (88, M8 = Me; M = Me; M = MMe; 8.88 e, 88.8 eeee) eee eeeee eeeeeeee ee e eeee ee eeeeeeeeeeeee (88, M8 = Me; 8.88 e, 88.8 eeee) eee eeeeeeee (8 eM, 88.8 eeee) ee eeeeeee (888 eM) ee 88°M. Mee eeeeeee eee eeeeee ee 88°M eee 8 e eee eeeeeee ee eeee ee 88°M. Mee eeeeeeeeeee eee eeeeeeeee eee eeeeeeeeeeee (MeMM); eeeee: 8.8 e (88%); ee 888–888°M.
8-(Meeeeeeeeeeee)-8,8-eeeeeeeeeeeeeee-8-eee-8-eeeee (88, M8 = MMe8; M8 = M8 = Me):[888]
Meeee(eeeeee)eeeeee eeeeeeee (88, M8 = Me; M = Me; 8.8 e, 8 eeee) ee MMMe8 (88 eM) eee eeeee eeeeeeee ee e eeeeeee eeee ee M,M-eeeeeeee-M′-eeeeeeeeeeeeee (88, M8 = MMe8; M8 = Me; 8.88 e, 8 eeee) ee eee MMMe8 (88 eM). Meeee 8 eee, Me8M (8.88 e, 8 eeee) ee eee MMMe8 (8 eM) eee eeeee eeeeeeee eee eee eeeeeeeee eeeeee eeee eee eeeeeee eee 8 eee, eeeeee eeeee eeeeee eeee eee eeeee eeeeeeee ee M8M. Meeee eeeeeeeeee eee eeeeee (Me8MM8), eee MMMe8 eeee eee eeeeeee ee eeeeee ee 8–8 eM eee eee eeeeeeee ee Me8M eee eeeeeeeeee eeeeeee e eeeeee eeeee ee eeeeeeeeeee. Meeeeeeeee eee eeeeeee eeee Me8M eeee eeeeee, eeeeeeeee eeeeee, eeeee eeeeeeeeeeeeee (eeeeeee) ee eeeeee eeeeeee; eeeee: 8.88 e (88%); ee 888°M (eee). MMM ee eeeeeee (MMMMMMM: eeeeeee ee e eeeeeeeeeeeee) eee eeee ee eeee ee eee eeeeeee ee eee eeeee eeeeeeee.
References
| [91] | Meeeeeee, M. M. M.; Meeee, M. M.; Meeee, M. M.; Meee, M. M.; Meee, M. M.; Meeeee, M. M.; Meeeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [188] | Meeeee, M. M.; Meeeeeeee, M., Meee Meee. Meeee., (8888) 88, 888. |
| [190] | Meeeeeee, M., Meee Meee. Meeee., (8888) 88, 888. |
| [194] | Meeeeee, M. M.; Meeeee, M.; Meee, M. M.; Meeeee, M. M.; Meeeee, M. M., M. Mee. Meee., (8888) 88, 88. |
| [195] | Meeeeee, M. M.; Meeeeeeeee, M. Me.; Meeeeeeee, M. M.; Meeeeeeeeeeee, M. M., Me. Meeeee. Meee., (8888) 88, 888; Meee. Meeee., (8888) 88, 88888. |
| [196] | Meeeeeeeeeee, M. M.; Meeeeeeeee, M. M., Meee. Meeeeeeeeee. Meeeee., (8888) 888; Meee. Meeee., (8888) 88, 88888. |
| [197] | Meeee, M. M.; Meee, M. M.; Meee, M.; Meeeeeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [198] | Meeeeeeee, M. M.; Meeeee, M. M.; Meeee, M., Meeeeeeee, (8888), 888. |
| [199] | Meeeee, M.; Meeeeee, M.; Meeeeeeeee, M.; Meeeee, M.; Meeee, M. M.; Meeéeee, M. M.; Meeeeeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [200] | Meeeeeeee, M.; Meeeeeeeee, M., Meee. Mee., (8888) 888, 8888. |
| [201] | Meeeeee, M.; Meee, M.; Meee, M., Meeeeee. Meee., (8888) 888, 8888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) 8, 888.
- 8.Meeeee-Meee, (8888) M 8, 888.
- 8.Meeeee-Meee, (8888) M 8-8, 8888.
- 8.Meeeee-Meee, (8888) M 8e, 888.
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