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12.1.2 Synthesis by Ring Transformation

DOI: 10.1055/sos-SD-012-00002

Stanovnik, B.; Svete, J.Science of Synthesis, (200212124.

Various (hetero)cyclic compounds, especially acyl-substituted heterocycles, are actually cyclic analogues of 1,3-dicarbonyl compounds or their synthetic equivalents. This makes them suitable substrates for the preparation of pyrazoles by treatment with hydrazine hydrate and substituted hydrazines. In most cases, syntheses of pyrazoles from suitably substituted heterocycles are closely related to the preparation of pyrazoles from 1,3-dicarbonyl compounds and hydrazine derivatives (see also Section 12.1.1.2.1.1).


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