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Please login or sign up for a free trial to access the full content. Method 1: With Carboxylic Anhydrides

DOI: 10.1055/sos-SD-012-00002

Stanovnik, B.; Svete, J.Science of Synthesis, (200212188.

Acetylation with acetic anhydride is carried out either at higher temperatures (100140°C) or in a mixture of acetic anhydride and pyridine at 90100°C giving 1-acetylpyrazoles 449 (Scheme 249).[‌293‌,‌750‌,‌819‌]

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