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Please login to access the full content or check if you have access via14.3.1.1.2.7.2 Variation 2: Of Glycine Derivatives and Active Methylene Compounds to Enamino Ketones
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Afarinkia, K.; Vinader, V., Science of Synthesis, (2003) 14, 288.
Addition of glycine derivatives to enamino ketones such as 31 (Scheme 25) is a convenient method for the preparation of 3-amino-2H-pyran-2-ones.[101,102] Additions of active methylene compounds to β-chloro enones,[103–105] e.g. 32, and β-ethoxy enones, e.g. 33, have also been investigated.[106] Addition of malononitrile[107] and ethyl acetoacetate[108] have also been reported, the latter for example to give 34 (Scheme 26).
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Meeeee 88 Meeeeeeee ee 8-Meeeee-8-eeeeee-8M-eeeee-8-eee[888]
Meeeeeeeeeee Meeeeeeee
8-Meeeee-8-eeeeeeeeeee-8-eee (88); Meeeeee Meeeeeeee:[888]
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References
[101] | Meee, M.; Meeeeee, M.; Meeeee, M., M. Meeeeeeeee. Meee., (8888) 88, 8888. |
[102] | Me-Meeee, M.; Me-Meeeee, M.; Meeee Meeeee, M. M.; Meee, M.; Me-Meeee, M. M.; Meeeeee, M. M., M. Meee. Mee., Meeee., (8888), 88. |
[103] | Meeee, M. M.; Meeeeee, M.; Meeeee, M., M. Meee. Mee., Meeee., (8888), 888. |
[104] | Meeeeee, M., Meeeeee. Meeee. Meee. Meeeee., (8888) 88, 8888. |
[105] | Meeeee, M.; Meeee, M. M., Mee. M. Meee., (8888) 88, 888. |
[106] | Meeeeeeeee, M.; Meeeeeeee, M.; Meeeee, M. M.; Meeeee, M., Meeeeee. Meeee. Meee. Meeeee., (8888) 88, 8888. |
[107] | Meeee, M.; Meeee, M.; Meeeeee, M.; Meeeeee, M., M. Mee. Meee., (8888) 88, 8888. |
[108] | Meeeeeee, M.; Meeee, M.; Meeeee, M.; Meeeee, M.; Meee, M.; Meeeeeee, M., Meee. Meeee. Meee., (8888) 88, 8888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) 8/8e, 8888.