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Please login to access the full content or check if you have access via14.4.1.1.1.2.2.3 Method 3: Reaction of 2-Hydroxybenzaldehyde Imines and Oximes and 2-Hydroxybenzamides with Carbon Suboxide
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Williams, A. C.; Camp, N., Science of Synthesis, (2003) 14, 371.
These reactions represent a very mild, general method for the preparation of functionalized 3-acyl-2H-1-benzopyran-2-ones 66–71. The mildness of the conditions, generally −70°C in diethyl ether, means that a wide range of substituents is tolerated (Scheme 22).[49,54,166–168]
Meeeee 88 Meeeeeeeeeeeee 8-Meee-8M-8-eeeeeeeeee-8-eeee ee Meeeeeee ee 8-Meeeeeeeeeeeeeeeeee Meeeee eee Meeeee eee 8-Meeeeeeeeeeeeeeee eeee Meeeee Meeeeeee[88,88,888–888]
Meeeeeeeeeee eeeeeeeee
8-Meeeeee-8-eee-8M-8-eeeeeeeeee-8-eeeeeeeeeee (88, M8 = M8 = M8 = M); Meeeeee Meeeeeeee:[888]
Meeeee eeeeeeee (8.8 e, 88 eeee) eee eeeeee eeeee ee e eeeeeee eeee ee 8-eeeeeeeeeeeeeeee (8.88 e, 88 eeee) ee eeeee eeeeeee (888 eM) ee −88°M. Meee eee eeeeeeee eee eeeeeeee eee eeeeeee eee eeeeeee ee 8°M eee 8 e eee ee eee 88 e. Mee eeeeeee eee eeeeeee eeeee eeeeeee eeeeeeee eee eee eeeeeee eeeeeeeeeeeeee [eeeeeeeee eeeee (ee 88–88°M)/Me8M] ee eeeeee eee eeeeeee; eeeee: 8.88 e (88%); ee 888–888°M.
References
| [49] | Meeeeeeeee, M.; Meeeeeeee, M.; Me-Meeeee, M.; Meee, M.; Meeeeee, M. M.; Mee, M.; Meeee, M.; Meeeeee, M.; Meeeee, M.; Meeee, M., Meeeeee, (8888) 88, 888. |
| [54] | Meeeeee, M.; Meeeeee, M.; Meeeeee, M.; Meeeeeeeee, M.; Meeeee, M.; Meeee, M., Meeeeee, (8888) 88, 888. |
| [166] | Meeeeee, M.; Meeeeeeeee, M.; Mee, M.; Meeeeeeee, M., Meeeeee, Me. Mee., (8888) 88, 888. |
| [167] | Meeeeeeeee, M.; Mee, M.; Meeee, M., Meeeeeeeeee Meee., (8888) 88, 8888. |
| [168] | Meeeeeeeee, M.; Mee, M., Meeeeeeeeeee, (8888) 88, 8888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) M 8-8, 8888.
- 8.Meeeee-Meee, (8888) M 88-8, 8888.
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