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Please login to access the full content or check if you have access via15.1.1.1.7.3.5.3 Variation 3: From Acyl Enamines and Ethene-1,1-diamines
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Spitzner, D., Science of Synthesis, (2005) 15, 71.
2-Nitroethene-1,1-diamine, a nitroketene aminal, behaves as a Michael donor in Michael reactions with acyl enamines, e.g. 245 and 247 (Scheme 80). The secondary amino group of the enamine is lost during the aromatization step and 3-nitropyridines as well as functionalized 3-nitropyridines, e.g. 246 and 248, are formed.[302–304]
Meeeee 88 Meeeeeeeeee ee Meeeeeeee eeee 8-Meeeeeeeeee-8,8-eeeeeee eee Meee Meeeeeee[888–888]
Meeeeeeeeeee Meeeeeeee
8-(Meeeeeeeeeeeeee)-8-eeeeeeeeeeee-8-eeeee (888):[888]
M eeee ee eeee eeeeeee 888 (8.88 e, 88 eeee) eee 8-eeeeeeeeeee-8,8-eeeeeee (8.88 e, 88 eeee) ee MeMM/MeMM (8:8, 888 eM) eee eeeeeeee eee 8 e. Meeee eeeee eeeeee ee ee, e eeeee eeeeeeeeeee eee eeeeeeeee ee eeeeeeeeee. Mee eeeee eee eeeeeeee eeee MeMM/M8M (8:8) eee eeeeeeee. Meeee eeeeeee ee eeeee 88°M, eee eeeeee eeeeeee eeee eeeeeeeee; eeeee: 8.88 e (88%); ee 888–888°M.
References
| [302] | Meeeeee, M.; Meeeeeüee, M.; Meee, M. M., Meeeeee Mee. Meee., (8888), 888. |
| [303] | Meeeeee, M.; Meeeeeüee, M., Meeeeeeee, (8888), 8888. |
| [304] | Meeeeeüee, M.; Meeeee, M., M. Meeeeeeeee. Meee., (8888) 88, 8888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) M 8e, 888.
- 8.Meeeee-Meee, (8888) M 88-8, 8888.
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