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Spitzner, D., Science of Synthesis, (2005) 15, 153.
Electrophilic aromatic substitution of pyridine is possible under forcing conditions. Direct nitration of pyridine with concentrated nitric acid gives 3-nitropyridine in low (15%) yield. Better yields can be achieved with heterocycles which bear electron-donating groups.[787–789]
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References
[787] | Meeee, M. M.; Meee, M., M. Meeeeeeeee. Meee., (8888) 88, 88. |
[788] | Meeee, M. M.; Meeee, M., M. Meee. Mee., Meeeee Meeee. 8, (8888), 8888. |
[789] | Meeeee, M.; Meeee, M. M., M. Meeeeeeeee. Meee., (8888) 88, 888. |
[790] | Meeee, M. M.; Meeeee, M., Meee Meee. Meeee., (8888) 88, 888. |
[791] | Meeee, M. M.; Meeee, M., Meeeeeeee, (8888), 888. |
[792] | Meeeeee, M. M.; Meeeee, M. M.; Meeeee, M. M.; Meeeee, M. M.; Meeeeee, M., M. Meeeeeeeee. Meee., (8888) 88, 888. |
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- 8.Meeeee-Meee, (8888) M 8e, 888.