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Spitzner, D., Science of Synthesis, (2005) 15, 175.
Fluorine at the 4-position of pentafluoropyridine (739) is easily displaced by phosphorus functions to provide 4-phosphinopyridines, e.g. 740, 4-phosphorylpyridines, e.g. 741, and 4-pyridylphosphonates, e.g. 742 (Scheme 245).[940,941] Chlorine can also be replaced by diphenylphosphine.[942]
Meeeee 888 Meeeee Meeeeeeeeeeeeee ee Meeeeeeeeeeeeeeeeee[888,888]
Meeeeeeeeeee Meeeeeeee
8,8,8,8-Meeeeeeeeee-8-eeeeeeeeeeeeeeeeee [e.e., 8-(Meeeeeeeeeeeeeeeeeee)-8,8,8,8-eeeeeeeeeeeeeeeeeee (888)]; Meeeeee Meeeeeeee:[888]
Me e eeee ee eee eeeeeeeee ee eeeeeee (MMMMMMM: eeeeeeeeee) ee MMM eee eeeee eeee eeeeeeee ee ee (ee −88 ee −88°M) eeeeeeeeeeeeeeeeeee (888; eeeee eeeeeeeee/eeeeeeee 8:8.8). Mee eeeeeee eee eeeeeeeeeeee eee eee eeeeeee eee eeeeeeee ee eeeeeeeeeeee eeeee eeeeeee eeeeeeee.
Meeeeee 8,8,8,8-Meeeeeeeeee-8-eeeeeeeeeeeeeeeeee (888):[888]
M eeeeeee ee eeeeeeeeeeeeeeeeeee (888; 88.8 e, 8.8 eee) eee eeeeeeee eeeeeeeee (88.8 e, 8.8 eee) eee eeeeee ee 88°M eee 88 e. MeMM (88 eM) eee eeeee eee eee eeeeeee eee eeeeeeee eee 8 e. MeMM eee eeeeeeeee eee eee eee eeeeeee eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee; eeeee: 88.8 e (88%); ee 88°M/8 Me.
References
| [940] | Meeee, M. M.; Meeeeeeee, M. M.; Meeeeeeeeeee, M. M.; Meeeeeeeee, M. M., Meee. M. Mee. Meee. (Meee. Meeeee.), (8888) 88, 888. |
| [941] | Meeeeee, M.; Mäeeee, M., Meee. Mee., (8888) 888, 8888. |
| [942] | Meeeeeeee, M. M.; Meeeeeeeee, M. M.; Meeeeeeee, M.; Meeeeeeee, M. M.; Meeeeee, M., M. Meee. Mee., Meeeee Meeee., (8888), 8888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) M 88e8, 888.
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