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Please login to access the full content or check if you have access via Variation 8: From N-Acetyl-2,2-dialkoxy-N-benzylethylamines

DOI: 10.1055/sos-SD-015-01146

Álvarez, M.; Joule, J. A.Science of Synthesis, (200515715.

Ring closure of N-acetyl-2,2-dialkoxy-N-benzylethylamines 199 is achieved with aluminum trichloride to give 2-acetyl-1,2-dihydroisoquinolines 200 (Scheme 91). In the published report, conversion into the aromatic system was not of interest and was not examined, although it seems likely that it could easily be achieved.[‌172‌]

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