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Please login to access the full content or check if you have access via15.5.1.1.1.5.2.1.4 Variation 4: From N-Acyl-2-arylvinylamines
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Álvarez, M.; Joule, J. A., Science of Synthesis, (2005) 15, 723.
In a few cases, Bischler–Napieralski-type closures have been achieved with unsaturated amides 223, producing the aromatic systems 224 directly (Scheme 102).[205–208] There are, however, no general, simple ways in which to prepare the starting unsaturated amides. The substrates 223 shown in Scheme 102 are prepared by acylation of an imine,[205] or thermolysis of a dihydrooxazole,[206] or reaction of aniline with an alkylideneoxazolone.[207]
Meeeee 888 Meeeeeeeeeeee eeee M-Meee-8-eeeeeeeeeeeeeee[888–888]
Meeeeeeeeeee Meeeeeeee
8,8-Meeeeeeeeeeeeeeeeeee (888, M8 = M8 = M; M8 = M8 = Me); Meeeeee Meeeeeeee:[888]
M-Meeeeee-8,8-eeeeeeeeeeeeeeeeee (888, M8 = M8 = M; M8 = M8 = Me; 8.8 e, 8.8 eeee) eee eeeeeee eeee M8M8 (8 e) ee eeeeeee (88 eM) ee eeeeee eee 8.8 e. Meee M8M8 (8 e) eee eeeee eee eeeeee eeeeeeeee eee 8.8 e. Mee eeeeeee eeee eee eeeeeeee eee eee eeeeeee eeeeee eeee eeeeeee (MMMMMMM: eeeeeeeeee). Mee eeeeeee eee eeeeeeeeee eee eee eeeeeee, ee Me8M, eeeeee eeee ee MeMM, eeeee, eee eeeeeeeeee ee eeee ee eee eeee eeeeeeeeeeee (MeMM) ee eeee eee eeeeeeeeeeee; eeeee: 8.88 e (88%); ee 88–88.8°M.
References
| [205] | Meeeee, M.; Meeeeee, M.-M., Mee. Meeee. Meee. Mee. M, (8888) 88, 8888. |
| [206] | Meeeeeeeee, M.; Meeeee, M. M., M. Meee. Mee., Meeee., (8888), 888. |
| [207] | Meeeeeeee, M.; Meeeee, M.; Meeeíe, M. M.; Meeéeeee, M., Meeeeeeeeeee, (8888) 88, 8888. |
| [208] | Meeeeeee, M. M.; Meeeeeeeeeee, M. M.; Meeeeee, M. M., Meee. Meeeeeeeee. Meeee. (Meee. Meeeee.), (8888), 8888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) M 8e, 888.
- 8.Meeeee-Meee, (8888) M 8e, 888.
- 8.Meeeee-Meee, (8888) M 88e8, 888.
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