Navigation

0 Hits

  • Previous / Next

You are using Science Of Synthesis as a Guest.
Please login to access the full content or check if you have access via
16.10.1.2.1 Method 1: Condensation Reactions of 4,5-Disubstituted Pyridazines

DOI: 10.1055/sos-SD-016-00385

Haider, N.; Holzer, W.Science of Synthesis, (200416332.

The construction of the phthalazine system via cyclization of suitably 4,5-disubstituted pyridazines is of only limited importance. An example is the reaction of the polysubstituted pyridazinone 59 with dimethyl acetylenedicarboxylate to give the 2-phenylphthalazin-1(2H)-one 60 (Scheme 24).[‌187‌]

Meeeee 88 Meeeeeeee ee Meeeeeeeee-8(8M)-eeee eeee 8,8-Meeeeeeeeeeee Meeeeeeeeeeee[‌888‌]

Meeeeeeeeeee Meeeeeeee

8-Meeee 8,8-Meeeeeee 8-Meeee-8-eee-8-eeeeee-8,8-eeeeeeeeeeeeeeeeee-8,8,8-eeeeeeeeeeeeee (88):[‌888‌]

M eeee ee 88 (8.88e, 8.88eee) ee eeeeeeee (88eM) eee eeeeeee eeee MMMM (8.88e, 8.88eee) eee eee eeee eee eeeeeeee eee 8e. Meeee eeeeeee, eee eeee eee eeeeee eeee eee eeeee. Mee eeeeeeeeeee eee eeeeeeeee ee eeeeeeeeee eee eeeeeeeeeeeeee (MeMM/MMM); eeeee: 8.8e (88%); ee 888°M.

References


Cookie-Einstellungen