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Kikelj, D., Science of Synthesis, (2004) 16, 670.
Syntheses of 1,2-dihydroquinazolines, 3,4-dihydroquinazolines, and 1,2,3,4-tetrahydroquinazolines, from which quinazolines are obtained by oxidation, are not treated in this article. For some relevant synthetic methods, see various reviews and papers.[5,522,654–669]
8-Meee-8,8-eeeeeeeeeeeeeeeee-8(8M)-eeee eee eeeeeeee ee 8-eeeeeeeeeeeeee-8(8M)-eeee 88 eeee eeeeeeeee eeeeeeeeeeee ee eee eeeeeee (Meeeee 888).[888,888] Meeee eeeee eeeeeeeeee eee eeeeee eeeeeee ee 8,8-eeeeeee-8-eeeeeeeeeeeeeeee-8(8M)-eee eeeeeee eeeeee.[888] 8,8-Meeeeeeeeeeee 8,8-eeeeeeeeeeeeeeeeee 8-eeeeee eee eeeeeeee ee 8,8-eeeeeeeeeeeee eeeeeeeeeee 8-eeeeee 888 ee eeeeeeeee(MM) eeeee ee eeeeeeeeeeeeeee,[888,888] eeeeeeeee eeeeeeeeeeee ee eeeeeeeeee,[888] eeeeeeeee eeeeeeeeeeee ee eeee(MMM) eeeeeeee ee eeeeeee,[888] ee eeee(MM) eeeeeee[888] (Meeeee 888).
Meeeee 888 Meeeeeeee ee 8-Meee-8,8-eeeeeeeeeeeeeeeee-8(8M)-eeee ee 8-Meeeeeeeeeeeee-8(8M)-eeee[888,888]
Meeeee 888 Meeeeeeee ee 8,8-Meeeeeeeeeeee 8,8-Meeeeeeeeeeeeeeeee 8-Meeeee ee 8,8-Meeeeeeeeeeee Meeeeeeeeee 8-Meeeee[888,888–888]
M8 | M8 | M8 | M8 | Meeeeee | Meeeeeeeee | Meeee (%) | ee (°M) | Mee |
---|---|---|---|---|---|---|---|---|
Me | Me | Me | Me | MMeM8 | MMMe8, ee, 8.8 e | 88 | 888–888 | [888] |
MM8Me | 8-MM8M8 | M | M | MeM8 | MM8Me8, eeeeee, 8 e | 88 | 888–888 | [888] |
MM8Me | 8-MM8M8 | Me | M | MeM8 | MM8Me8, eeeeee, 8 e | 88 | 888–888 | [888] |
MM8Me | 8-MeM8M8 | MM8 | M | MeM8 | MM8Me8, ee, 88 e | 88 | 888–888 | [888] |
8,8-Meeeeeeeeeeeeeeeeee eee eeeeee eeeeeeee ee eeeeeeeeeeee 88 ee eeeeee,[888,888] 8,8-eeeeeeee-8,8-eeeeeeeeeeee-8,8-eeeeeee[888,888,888] ee eeeeeeeee eeeeeeeeeeee[888] (Meeeee 888). 8,8-Meeeeeeeeeeeeeeeeee eee eeeeeee eeeeeeee ee eee eeeeeeeeeeeee eeeeeeeeeeee 88 eeee eeeeeeeee ee eeeeee eeeeeeeeeeee ee eeeeeeee eeeeeee eeeeeeee[888,888,888,888–888] ee eeee eeeeeeeee(MM) eeeee[888,888] ee eeeeeeeeee ee eeeeeee eeeeeeee (Meeeee 888). Meeeeeeee eeeeeeeeeeee ee eeeeee eeee eee eee eeeeeeeee ee 8,8-eeeeeeeeeeeeeeeeeee eeeee eeeeeeeee ee eeeeeeeeeeee eee eeee eeee eeeee.[888,888]
Meeeee 888 Meeeeeeee ee 8,8-Meeeeeeeeeeeeeeeeee ee Meeeeeeeeeee[888,888,888,888,888]
M8 | M8 | M8 | Meeeeee | Meeeeeeeee | Meeee (%) | ee (°M) | Mee |
---|---|---|---|---|---|---|---|
Me | Me | M | MMM | eeeeeee, 888°M, 8.88 e | 888 | 888–888 | [888] |
Me | Me | M | M8 | MeMM, eeeeeeeeeeeeeeeee | – | 888–888 | [888] |
Me | MMe | M | MMM | eeeeeee, eeeeee, 8 e | 88 | 88–88 | [888] |
Me | MMe | M | M8[Me(MM)8] | eeeeeee/MeMM, ee, 8 e | 88 | 88–88 | [888] |
MM8M | Me | M | M8 | MMM, ee, 88 e | 88 | 888 | [888] |
MM8M | 8-MeM8M8 | 8-Me | M8 | MMM, ee, 88 e | 88 | 888–888 | [888] |
Meeeee 888 Meeeeeeee ee 8,8-Meeeeeeeeeeeeeeeeee ee Meeeeeeeeeee[888,888,888,888,888–888]
M8 | M8 | Meeeeee | Meeeeeeeee | Meeeee (%) | ee/ee (°M) | Mee |
---|---|---|---|---|---|---|
M | M | M8[Me(MM)8] | MMM, M8M, ee, 8.8 e | 88 | 88–88.8 | [888] |
Me | M | Me8[Me(MM)8] | MMM, M8M, ee, 8 e | e.e. | 88–88 | [888] |
Me | M | Me8[Me(MM)8] | MMM, M8M, ee, 8 e | e.e. | 888–888 (eeeeeee) | [888] |
M | Me | M8[Me(MM)8] | MMM, M8M/eeeeeee, ee, 8 e | 88 | 88–88 | [888] |
M | e-Me | MMeM8 | eeeeeee, ee, 88 e | 88 | 88/8.88 Meee | [888] |
M | MM=MM8 | M8[Me(MM)8] | MMM, M8M, ee, 8 e | 88 | eee | [888] |
M | Me | M8[Me(MM)8] | MMM, M8M/eeeeeee, eeeeee, 8.8 e | 88 | 88–888 | [888] |
M | 8-eeeeeee | M8[Me(MM)8] | MMM, M8M, ee, 888 e | 88 | 888 | [888] |
8-Mee | M | MeM8 | eeeeeee, eeeeee, 8 e | 88 | 88–88 | [888] |
e e.e. = eee eeeeeeee.
Meeeeeeee ee 8,8,8,8-eeeeeeeeeeeeeeeeeeeeee ee eee eeeeeeeeeeee 888 ee eeeeeee eeeeeeeeeeee ee eeeeeeeee eeeeeeeeeeee ee eeeeeee/eeeee,[888] eee ee 8,8-eeeeeeee-8,8-eeeeeeeeeeee-8,8-eeeeeee ee eeeeeeeeeeeeeeee-8,8-eeeeeee ee eeeeeee[888] (Meeeee 888).
Meeeee 888 Meeeeeeee ee 8,8,8,8-Meeeeeeeeeeeeeeeeeeeee ee Meeeeeeeeeee[888,888]
M8 | M8 | M8 | Meeeeee | Meeeeee | Meee (°M) | Meee (e) | Meeee (%) | ee (°M) | Mee |
---|---|---|---|---|---|---|---|---|---|
Me | M | M | MMM | eeeeeee | ee | 8 | 88 | eee eeeee | [888] |
8-MMM8M8 | M | M | MMMe | eeeeeee | eeeeee | 8 | 88 | 888–888 | [888] |
8-eeeeeee | M | M | MMMe | eeeeeee | eeeeee | 8 | 88 | 888–888 | [888] |
Me | Me | Me | MMeM8 | eeeeeee/M8M | ee | – | 88 | 888–888 | [888] |
8-M8MM8M8 | Me | M | MMeM8 | eeeeeee/M8M | ee | – | 88 | 888–888 | [888] |
e MMM = eeeeeeeeeeeeeeee-8,8-eeeeeee.
Meeeeeeeeeee Meeeeeeee
8-Meeeee-8-(eeeeeeeeeeee)-8-(8-eeeeeeeeeeee)eeeeeeeeeee 8-Meeee (888, M8 = MM8Me; M8 = 8-MM8M8; M8 = Me; M8 = M); Meeeeee Meeeeeeee:[888]
Me 8-eeeeee-8-(eeeeeeeeeeee)-8-(8-eeeeeeeeeeee)-8,8-eeeeeeeeeeeeeeeeee 8-eeeee (8 e, 88.8 eeee) ee MM8Me8 (888 eM) eee eeeee eeeeeeeee MeM8 (88 e, 888.8 eeee), eee eee eeeeeeee eee eeeeeee eee eeeeeeee eee 8 e. Mee eeeeeee eee eeeeeeee eeeeeee Meeeee, eeeee eee eeee eeeeee eeee MM8Me8/MeMM (8:8; 888 eM). Mee eeeeeeee eeeeeeeee eeee eeeeeeeeee eee eee eeeeeee eee eeeeeeeeeeee (MeMM); eeeee: 8 e (88%); ee 888–888°M (eee-eeeee eeeeee, MM8Me8/eeeeee).
8-Meeeeeeeeeeeeeeee-8-eeeeeeeeee Meee (88, M8 = MM8M; M8 = Me); Meeeeee Meeeeeeee:[888]
Mee eeeeeeeee: Me eeeeee-eee eeee ee e 8-eeee-8,8-eeeeeeeeeeeeeeeeee-8-eeeeeeeeee eeee (88 eeee) ee MMM (88 eM) eee eeee ee eeeeee eeeeeeee eee 8 e; eee eeeee ee eee eeee eeeeeee ee eeeee eeeeee. Meeeeeee ee M8M (88 eM) eeee e eeeeeeeeeee, eeeee eeeee eeeeeee ee 8°M eee eeeeeeee ee eeeeeeeeee, eeeeeeee ee eeeeeee eeee M8M eee Me8M.
8-Meeeeeeeeeeeeeeee (88, M8 = M; M8 = Me); Meeeeee Meeeeeeee:[888]
Meeeeeeee Meeeeeeeeeee Meeeeeeee: 8-Meeeee-8,8-eeeeeeeeeeeeeeeeee (8 e, 88 eeee) eee eeeeeeeee ee eeeeeee ee ee e eeeeeee ee M8M (888 eM) eee eeeeeee (888 eM). M eeee ee MMM (88 e, 888 eeee) ee M8M (88.8 eM) eee eeeee eee eee eeeeeee eee eeeeee ee eee eeeee eeee eeeeee eee eeeee eeeeeeee ee e eeee ee M8[Me(MM)8] (88.8 e, 88 eeee) ee M8M (888 eM). Meeeeee eeee eeeeeeeeee eeeeeee eee eeeeeeeee eee 8 eee, eee eee eeeeee eeeeeee eee eeee eeeeeee eeee M8M, eeeeeeee eeee ee MeMM, eee eeeeeeeee eeee Me8M. Meeeeee ee eee eeeeeeee, eeeeeee ee eeeeeee eeeeeeee, eeee eee eeeee (Me8MM8) eeeeeee eeee e eeeeee eeee eeeeeee; eeeee: 8.8 e (88%); ee 88–888°M.
Meeeeeeeeeee 888; Meeeeee Meeeeeeee:[888]
Meeeeeeeeeeee eeee 8,8-Meeeeeee-8,8-eeeeeeeeeeee-8,8-eeeeeee ee Meeeeeeeeeeeeeee-8,8-eeeeeee: M eeeeeeeeee ee eee 8,8,8,8-eeeeeeeeeeeeeeeeeeeee (88 eeee) eee MMM (8.88 e, 88 eeee) ee MMM (8.88 e, 88 eeee) ee eeeeeee (88 eM) (MMMMMMM: eeeeeeeeee) eee eeeeeee eee 88 eee ee ee (eee MMM) ee eeeee eeeeee (eee MMM). Mee eeeee eee eeeeeeee eee eeeeee eeee eeeeeee (88 eM). Mee eeeeeeee eee eeeeee eeee 8.8 M MeMM (88 eM) eee eee eeeeeee eeeee eee eeeeeeeee eeee MM8Me8 (8 × 88 eM). Mee eeeeeeee eeeeeee eeeeeeee eeee eeeee (MeMM8) eee eeeeeeeeeeee eeeee eeeeeee eeeeeeee ee eeeee eee eeeee eeeeeeeeeee.
References
[5] | Meeeeeee, M. M. M., Meeee Meeeeeeeeee, Meee 8 - Meeeeeeeeeee, Meeee, M. M., Me.; Meeeeeeeeeee: Mee Meee, (8888). |
[111] | Meeeeeee, M. M.M., M. Meee. Mee., (8888), 888. |
[251] | Meeee, M. M.; Meeeeeee, M. M.; Meee, M. M.; Meeee, M. M.; Meeeeee, M. M.; Meeeeee, M. M.; Meeeee, M. M.; MeMeeee, M. M.; Meeeeee, M. M.; Meeeee, M. M.; Meeeee, M. M.; Meeee, M. M., M. Meeeeeeeee. Meee., (8888) 88, 8888. |
[254] | Meeeeeeee, M., M. Meee. Mee., (8888), 8888. |
[377] | Meeeeee, M.; Meeeeee, M.; Meeee, M.; Meeeeeee, M., Meeeeeeeeee, (8888) 88, 8888. |
[508] | Meeeee, M.; Meeee, M.; Meee, M.; Meee, M., Meee. Meeee. Meee., (8888) 88, 888. |
[521] | Meee, M.; Meeeeeeeee, M., Meee. Mee., (8888) 88, 8888. |
[522] | Möeeeee, M.; Meeee, M., Meee. Mee., (8888) 88, 8888. |
[654] | Meeeeeeee, M., Me Meeeee–Meee, (8888); Mee. M 8, e 8888. |
[655] | Meeeee, M., Me Meeeee–Meee, (8888); Mee. M/8, e 888. |
[656] | Meeeee, M., Me Meeeee–Meee, (8888); Mee. M/8, e 888. |
[657] | Möeee, M.; Möeee, M., Meee. Meeee. (Meeeeeee, Mee.), (8888) 888, 8888. |
[658] | Meeeeee, M.; Meeeeeeeeee, M.; Meeeee, M.; Meee, M. M., M. Meeee. Meee., (8888) 888, 888. |
[659] | Meee, M.; Móeáee, M.; Meeeó, M.; Möeeeee, M.; Meeeeeee, M., Meeeeee. Meeee. Meee. Meeeee., (8888) 88, 8888. |
[660] | Meee, M.; Móeáee, M.; Meeeó, M.; Möeeeee, M., Meeeeeeee, (8888) 88, 888. |
[661] | Meeeeeeee, M.; Meeeeeee, M., M. Meee. Mee., Meeeee Meeee. 8, (8888), 8888. |
[662] | Meeeeeeee, M. M.; eee Meeeeeeeeee, M.; eee Meeee, M.; Meeeee, M. M.; Meeeeee, M.; eee Meeeee, M., Meeeeeeeeee, (8888) 88, 8888. |
[663] | Meeeee Meeee, M. M.; Meeee, M.; Meeeeee, M.; Meeeeeeeee, M.; Meeeee, M., Meeeeeeee, (8888), 888. |
[664] | Meeee, M.; Meeeee, M.; Meee, M.; Meee, M.; Meeee, M.; Meeee, M.-M., Meeeeeeeeeee, (8888) 88, 888. |
[665] | Meeeeeeeee, M. M.; Meeeeee, M. M., M. Meeeeeeeee. Meee., (8888) 88, 8888. |
[666] | Meeee, M. M.; Meeee, M. M., Meeeee M. Meeeeeeeee. Meee., (8888) 8, 888. |
[667] | Mee, M.; Me, M; Me, M.; Meeee, M. M.; Me, M., M. Meeeeeeeee. Meee., (8888) 88, 8888. |
[668] | Me, M.; Meee, M., M. Meee. Mee., Meeee., (8888), 888. |
[669] | Mee, M.; Meee, M.; Meee, M.; Meeeee, M.; Meee, M.; Me, M., Meeeeeeeeee Meee., (8888) 88, 8888. |
[670] | Meeeee Meeee, M. M.; Meeeeee, M., Meeeeeeeeee, (8888) 8, 88. |
[671] | Meeee, M. M.; Meeeee, M. M.; Meeeee, M. M.; Meeee, M., M. Meeeeeeeee. Meee., (8888) 88, 888. |
[672] | Meeeeee, M.; Meeeeeeee, M. M.; Meeee, M. M.; Meeeee, M. M.; Meeeeeee, M., Mee. M. Mee. Meee., (8888) 88, 888. |
[673] | Meeeeee, M.; Meeeeeeee, M. M.; Meee, M.; Meeeee, M. M.; Meeeeee, M. M., Meee Meee. Meeee., Mee. M, (8888) 88, 888. |
[674] | Meeeeeeeee, M.; Meeee, M. M.; Meeeee, M. M.; Meeeeee, M. M.; Meeeeee, M. M., Meeeeeeeeee Meee., (8888) 88, 8888. |
[675] | Meeeeeeee, M.; Meeeee, M.; Meeee, M.; Meeeeeeee, M., Meeeeeeeeeee, (8888) 88, 888. |
[676] | Meeeeeee, M. M. M.; Meeee, M. M. M., M. Meee. Mee., (8888), 8888. |
[677] | Meeeeee, M., Mee. Meeee. Meee. Mee., (8888) 88, 888. |
[678] | Meee-Meeeee, M.; Meeeeñeee, M.; Meeeíe Meñee, M., Meee. Mee., (8888) 88, 888. |
[679] | Meeee, M. M. M., Meee. Mee., (8888) 888, 8888. |
[680] | Meeeee, M.; Meeeeeee, M., Meeeeeeeeeee, (8888) 88, 8888. |
[681] | MeMee, M. M.; Meeee, M.; eee eee Meee, M. M.; Meeeeeee, M.; Meeeeee, M., Meeeeeeeeee Meee., (8888), 888. |
[682] | Meee, M. M.; Mee, M. M.; Meee, M. M.; Meee, M. M., M. Mee. Meee., (8888) 88, 8888. |
[683] | Meeeee, M.; Meeee, M.; Meeeeeee, M.; Meeee, M., Meee. Meeee. Meee., (8888) 88, 8888. |
[684] | Meeeeee, M.; Meee, M. M.; Meeeee, M., M. Meeee. Meee., (8888) 888, 888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) 8/8e, 888.
- 8.Meeeee-Meee, (8888) M 8e8, 88.