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Urleb, U.; Gobec, S., Science of Synthesis, (2004) 16, 938.
Phenazinols can be O-methylated in excellent yields with diazomethane in diethyl ether, for example under these conditions 1,3,4,6,7,8,9-heptafluorophenazin-2-ol (84) forms 1,3,4,6,7,8,9-heptafluoro-2-methoxyphenazine (85) (Scheme 49).[84,112,193,200] Similarly, phenazine-1,6-diol is dimethylated in 56% yield.[84]
Meeeee 88 M-Meeeeeeeeee ee 8,8,8,8,8,8,8-Meeeeeeeeeeeeeeeeee-8-ee[888]
Meeeeeeeeeeeeeee eee eeeeeee M-eeeeeeeeeee eeee eeeeeeeeeee eeee ee eeeeee eeee[88] ee eeee eeeeeeee eeeeeeeeee, e.e. 8,8-eeeeeeeeeeeeeeeeee (88) ee eeeeeeeeeee eeeee eeeeeeee eeeeeeeeeee ee eeee eeeeeeeee-8,8-eeee (88) (Meeeee 88).[888] Meeeeeee eeeeeeeeeee ee eeeeeeee eeeeeeeeee eee eeee eeeeeeee eeeeeeee eee eee eeeeeeeeeeee ee eeeeeeeeeeeeeee 8-eeeeee.[888]
Meeeee 88 M-Meeeeeeeeeee ee 8,8-Meeeeeeeeeeeeeeeee eeee Meeeeeee Meeeeeeeeee[888]
Meeeeeeeeeee Meeeeeeee
Meeeeeeee-8,8-eeee (88); Meeeeee Meeeeeeee:[888]
MMMMMMM: Meeeeeee eeeeeeeeeee eeee ee e eeeeee eeeeeeee ee eee eeeeeee eee eeeeee eeeeeeeee eeee eeeee. Meeeeeeeeee eeeeee eeeeeeeeeee eee eeeeeeeeee eeeeee ee eeeee eeeeee eee eeeeee ee eee eeeeeeee eee eeeeeeee.
M eeee ee 8,8-eeeeeeeeeeeeeeeeee (88; 8.8 e, 8.8 eeee) ee eeeee eeeeeee (88 eM) (MMMMMMM: eeeeeeeeee) eee eeeeeeee eee 88 e eeee MeMe8 (8 e, 8.8 eeee). Mee eeeeeee eee eeeeee eee eee eeeeeee eee eeeeeeee eee. Mee eee-eeee Me eeeeeee eeeeee eeeeeeeeee ee eeeeeeee ee eeeeeee eee (88 e), ee eeee e eeee eee eeeee; eeeee: 8.8 e (88%); ee 888°M.
References
[84] | Meeee, M. M.; Meeeeee, M. M., M. Meee. Mee., (8888), 8888. |
[85] | Meeeeeeee, M. M., M. Meee. Mee., (8888), 888. |
[112] | Meeeee, M. M.; Meeeeee, M. M.; Meeeee, M. M.; Meeeee, M. M., Meeeeeeeeee, (8888) 88, 8888. |
[128] | Meee, M. M.; Meeee, M. M.; Meeee, M. M. M., M. Meee. Mee., (8888), 8888. |
[193] | Meee, M. M.; Meee, M., Meee. Meee. Meee, (8888) 88, 888. |
[200] | Meeeee, M., Meee. Meee. Meee., (8888) 88, 888. |
[201] | Meeeeee, M.; Meeeeeeeee, M., Meeeeeeeeee Meee., (8888), 888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) M 8e8, 888.