You are using Science Of Synthesis as a Guest.
Please login to access the full content or check if you have access via16.17.1.1.2 Method 2: Synthesis of 7-Substituted Purines
Please login to access the full content or check if you have access via
Seela, F.; Ramzaeva, N.; Rosemeyer, H., Science of Synthesis, (2004) 16, 965.
Reaction of (alkylamino)acetonitriles or (arylamino)acetonitriles with formimidamide acetate gives 7-substituted purines 15 in relatively good yield (Scheme 17).[168]
Meeeee 88 8-Meeeeeeeeee Meeeeee eeee (Meeeeeeeee)eeeeeeeeeeeee ee (Meeeeeeee)eeeeeeeeeeeee eee Meeeeeeeeeeee Meeeeee[888]
| M8 | Meee, Meee | Meeee (%) | Mee |
|---|---|---|---|
| Me | 888°M, 8 e | 88 | [888] |
| Me | 888–888°M, 8 e | 88 | [888] |
| MM8MM8MM | eeeeee, 8 e | 88 | [888] |
| Me | eeeeee, 8 e | 88 | [888] |
| 8,8-Me8M8M8 | eeeeee, 8 e | 88 | [888] |
Meeeeeeeeeee Meeeeeeee
8-Meeeee-8M-eeeeee (88, M8 = Me) :[888]
M eeeeeee ee (eeeeeeeeeee)eeeeeeeeeeee (8.8 e, 8.88 eeee), eeeeeeeeeeeee eeeeeee (88.8 e, 8.88 eee), eee eeeeeeeee (88 eM) eee eeeeee ee 888°M eee 8 e eee eeee eeeeeeeeee ee eeeee ee eeeeeee. Mee eeeeeee eee eeeeeeeee ee eee M8M (88 eM) eee eeeeeeeee eeee MMMe8. Mee MMMe8 eeeeeee eee eeeeeeeeee ee eeeeeee, eee eee eeeeeee eee eeeeeeee eee eeeeeeeeeeeeee [eeeeeee (MMMMMMM: eeeeeeeeee)]; eeeee 8.8 e (88%); ee 888–888°M.
References
| [168] | Meeeeeeee, M.; Meeeeeeeeee, M.; Meeeee, M., Meeeee Meeeeee Mee. Meee., (8888) 888, 88. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) M 8e8, 888.
Return to Top