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DOI:
10.1055/sos-SD-016-01192
Seela, F.; Ramzaeva, N.; Rosemeyer, H., Science of Synthesis, (2004) 16, 1072.
Modified purines containing carbon substituents in the 2-, 6-, or 8-position are associated with interesting biological properties such as antiviral, anticancer, antihypertensive, or cytokinin activity. There are several methods for the introduction of an alkyl, alkenyl, or alkynyl group into the purine ring depending on the nature of the reagent used for the displacement reaction and the mechanism of the reaction.
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