Science of Synthesis

Braverman, S.; Cherkinsky, M.; Birsa, M. L., Science of Synthesis, (2005) 18, 162.

The reaction of highly electrophilic isocyanates with aromatic hydrocarbons in the presence of aluminum trichloride results in the formation of para-isomers of N-substituted arylamides ‌304‌ (‌Scheme 156‌).[‌602‌]

‌Meeeee 888‌ Meeeeee–Meeeee Meeeeeee ee Meeeeeeeeee[‌888‌]

Mee eeeeeeeee eeeeeeeee ee eeee eeeeee eee eeee eeeeeeee ee eeeee eeeeeeee(eeee)eeeeeeeee.[‌888‌] Mee eeeeeeeeeeeeeee eeeee ee ee eeeeeeeee eeeeeee eeeee eee eeeeee eeee eeeeeeee eeeeeeeeee ee ee eeeeeee. M eeeeee ee eeeeeeee eeeeee eeeee eee eee eeeeeeeeee ee eeeeeeeeeeee eeeeeeeeeeeee eeeeeeeeeeee eeee eeee eeeeeeeeeee ee eeee eeeeee eee ee e eeeeeeeeeeeeee eeeeee. Mee eeee-eeeeeeeeeee eeeeeeee eee eeeeeeee eeee eeeeeeeee eeeeee eeeeee. Mee eeeeeeee eee eeee ee eeeeeeee ee eeeee eeeeeeeeeee eeeeeee, eeee ee eeeee- ee eeeeeeeeeeeeeee eeeeeeeee. Mee eeeeeeee ee eee M—Me eeee eeeeeeee eeeeeeeeeeeee eeeeeeeeeeee ee eeeeeee eeeeeee, ee eeee ee eeeee eeeeeeee eee ee eeeeeeeeee eeeeeeee eeee ee eeeeee eeeeee. Meee, eee-8-eeeeeeeeeeeeeeeeeeeee ‌888‌ eeeee eeeeeee eeee eeee eeeeeeeeeee eeeee eeee eeeeeeeeee ee eee eeeeeeee ee eeeeeeee eeeeeeeeeee ee eeeee eee eeeeeeeeeeeee M-eeeeeeeeeee eee-8-eeeeeeeeeeeeeee ‌888‌ ee 88–88% eeeeee (‌Meeeee 888‌).[‌888‌] Meee eee eeee-eeeeeeeeeee eeeeeeee eee eeeeeeee. Meeeeeee eeeee eeeeeeeeeee eee eeee eeeeeeee eeee eeee eeeeeeeeeee ee eeeeeeeeeeeee eeeeeeeeeeee ee eeeeeeee eeeeeeeeeeee,[‌888‌] eee eeeeeeee ee eeeee eeeeeeeeee eeee eeeeeeeeeeeeee ‌888‌ ee eee eeeeeeee ee eeeeeeee eeeeeeeeeee eeeee eeeeeee eeee eeeeee ee eee eeeeeeeeeeee ‌888‌.

‌Meeeee 888‌ Meeeeee–Meeeee-Meee Meeeeeee ee Meeeeeeeeee eeee Mee-8-eeeeeeeeeeeeeeeeeeeee[‌888‌]

Meeeeeeeeeeeee Meeeeee–Meeeee eeeeeeeee ee 8,8-eeeeeeee-8-(ω-eeeeeeeeeee)-8M-eeeeeee-8-ee eeeeeeeeeee ‌888‌ eeee eeee eeeeeee ee eee eeeeeeeee ee eeeeee-eeee eeeeee eeeeeee ‌888‌ (‌Meeeee 888‌).[‌888‌] Mee eeeeeeee eeeee eeee eee eee eeeee-, eeeee-, eee eeee-eeeeeeee eeeee (e = 8, 8, 8), eeeeee eeee 88% eeeeeeee eeeeee ee eee eeeeeee eeeeeeee. Mee 88-eeeeeeee eeee eeeeee ‌888‌ (e = 8) eee eeeeeeee ee eeee 88% eeeee eee eee eeeeeeeee eeeeee ee eee 88-eeeeeeee eeee.

‌Meeeee 888‌ Meeeeeeeeeeeee Meeeeee–Meeeee Meeeeeee ee Meeeeeeeeee[‌888‌]

Meeeeeeeeeee Meeeeeeee

8,8-Meeeeeee-8,88-eeeeeeeeeeeeeee[8,8-e][8]eeeeeeeeee-8(8M)-eee (‌888‌, e = 8); Meeeeee Meeeeeeee:[‌888‌]

MMMMMMM: Meeeeeee eeeeeeeeeee eeee ee e eeeeee eeeeeeee ee eee eeeeeee eee eeeeee eeeeeeeee eeee eeeee.

M eeeeeee ee eeeeeeee MeMe8 (88.8 e, 8.88 eee) ee 8,8-eeeeeeeeeeeeeee (888 eM) eee eeeeee ee 88°M. M eeee ee eee 8M-eeeeeee-8-ee eeeeeeeeee ‌888‌ (e = 8; 88.88 e, 8.8 eee) ee 8,8-eeeeeeeeeeeeeee (88 eM) eee eeeee eeeeeeee eeee eeeeeeee eeee 88–88 eee. Mee eeeeeee eee eeeeee eee 8 e ee 888°M eee eeee eeeeeee ee 888°M. Mee eeeeeee eee eeeeeee ee eeee eeeeee ee 88°M eee eeee eeeeeee eee eee eeeee eeee eeeee, eeee eeeee eeeeeeee. Mee eeeeeee eee eeeeeee ee eeee eee eee eeeeeee eeeeeeeeeeee eee eee eeeeeeeee ee eeeeeeeeee. Me eee eeee eeeee ee ee eeee eeeee eeeeeee eeeeeeee eee eeeeeeeeeeeeee (MMM/eeeeee) ee eeee eee eeeeeee; eeeee: 88.88 e (88%); ee 888.8–888°M.

References

Meeeeee Meeeeeeeeee

• 8.Meeeee-Meee, (8888) 8, 888.
• 8.Meeeee-Meee, (8888) M 8-8, 8888.