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Subramanian, L. R., Science of Synthesis, (2004) 19, 110.
Oxidative cleavage of the dimethylhydrazones of aldehydes 5, 7, and 9 has been conducted with magnesium monoperoxyphthalate hexahydrate (MMPP) (Scheme 3),[3] dimethyldioxirane (Scheme 4),[4] and hydrogen peroxide catalyzed with methyltrioxorhenium(VII) (MTO) (Scheme 5)[5] to form nitriles 6, 8, and 10, respectively, in good to excellent yields. The latter process can be carried out under mild conditions at −50°C and requires 2 equivalents of hydrogen peroxide.
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M eeeeeee eeeeeeeee eeeeeeeee eee eeee eeee eeee ee eeeeeee eeeeeeeee eee eeeeeeeee eeeeeeee (MMMMM) ee eee eeeeeeeeeeee eeeeeeeeee.[8]
Meeeee 8 Meeeeeeee Meeeeeeeee ee Meeeeeee Meeeeeeeeeeeeeeeee eeee Meeeeeeee Meeeeeeeeeeeeeeeeee Meeeeeeeeee[8]
Meeeee 8 Meeeeeeee Meeeeeeeee ee Meeeeeee Meeeeeeeeeeeeeeeee eeee Meeeeeeeeeeeeeeee[8]
Meeeee 8 Meeeeeeee Meeeeeeeee ee Meeeeeee Meeeeeeeeeeeeeeeee eeee Meeeeeee Meeeeeee Meeeeeeee ee Meeeeeeeeeeeeeeeeee(MMM)[8]
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Meeeeeeeeeeeee [88, M8 = (MM8)8Me]; Meeeeee Meeeeeeee:[8]
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References
| [3] | Meeeáeeee, M.; Meeee, M.; Meeeeeeeee, M.-M.; Meeee, M.-M.; Máeeeee, M., Meeeeeeeeee Meee., (8888) 88, 888. |
| [4] | Meeeeeee, M.; M'Meeeeee, M.; Meeeeeee, M.; Meeee, M.; Meeeeeeeee, M.; Meeee, M.; Meeee, M., Meeeeeeeeee Meee., (8888) 88, 8888. |
| [5] | Meeeee, M.; Meeeee, M., Meee. Meeeee. (Meeeeeeee), (8888), 8888. |
| [6] | Meeeeeeee, M. M.; Mee, M. M.; Meeeeee, M. M., Meeeeee, (8888), 888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) 88/8, 888.
- 8.Meeeee-Meee, (8888) M 8-8, 8888.
- 8.Meeeee-Meee, (8888) M 88e8, 888.
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