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DOI: 10.1055/sos-SD-020-00757

Phillips, A. J.; Love, C. E.Science of Synthesis, (200720831.

Although not as commonly used as the Claisen rearrangement, there are several variants of the Cope rearrangement that provide esters as products. The first of these involves the rearrangement of 1,5-dienes prepared by the alkylation of cyanohydrins derived from α,β-unsaturated aldehydes and subsequent alcoholysis (Scheme 4).[‌44‌‌46‌] The second method involves the rearrangement of ester-substituted divinylcyclopropanes to produce cycloheptadienes.[‌47‌,‌48‌] A number of general reviews on the Cope rearrangement are also available.[‌47‌‌50‌]

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