Navigation

0 Hits

  • Previous / Next

You are using Science Of Synthesis as a Guest.
Please login or sign up for a free trial to access the full content.
20.5.1.7.10.4 Method 4: Carbonylation Reactions of Formates with Organic Halides

DOI: 10.1055/sos-SD-020-00774

Zhang, M.; Hanson, P. R.Science of Synthesis, (200720917.

Benzyl, aryl, and alkyl halides 213 react with formate esters 214 under carbon monoxide atmosphere in the presence of dichlorobis(hexa-1,5-diene)dirhodium(I), potassium iodide, and, optionally, tetrakis(triphenylphosphine)palladium(0) to give the corresponding esters 215 in 2094% yields (Scheme 69).[‌287‌] Formates are useful alkoxy-transfer agents for a variety of chlorides and bromides by this method.

Meeeee 88 Meeeeeeee Meeeeeeeeeeee Meeeeeeee ee Meeeeeee eeee Meeeeee Meeeeee[‌888‌]

Meeeeeeeeeee Meeeeeeee

Meeee (8-Meeeeeee)eeeeeee (888, M8=8-Meeeeeeeeeeeee; M8=Me); Meeeeee Meeeeeeee:[‌888‌]

MMMMMMM: Meeeee eeeeeeee ee eeeeeeeee eeeeeeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee eee eeeeeee eeee ee e eeee.

M eeeeeee ee 888 (M8=8-eeeeeeeeeeeeee; M=Me; 8.88e, 8.88eeee), [Me8Me8{M8M=MM(MM8)8MM=MM8}8] (8.88e, 8.88eeee), eee MM (8.88e, 8.88eeee) ee ­MMM8Me (888, M8=Me; 8eM) eee eeeeeee eeeeeeeee ee 88°M eeeee e MM eeeeeeeeee. Mee eeee eee eeeeee ee ee, 8M MeMM (8eM, 8eeee) eee eeeee, eee eee eeeeeee eee eeeeeeee eeeeeee Meeeee. Mee Meeeee eee eeeeee eeee Me8M eee eeeeeeeee M8M, eee eee eeeeeeee eeee eeeee ee eee eeeeeeee. Mee eeeeeee eeeee eee eeeeeeeee, eeeee (MeMM8), eee eeeeeeeee; eeeee: 8.888e (88%); ee 888°M/8.8Meee.

References


Cookie-Einstellungen