Science of Synthesis

Whitehead, A.; Sieck, S. R.; Mukherjee, S.; Hanson, P. R., Science of Synthesis, (2005) 21, 924.

Vinylphosphonates can be prepared via perfluoroalkylsulfonyl enol ethers from an array of acylphosphonates.[‌55‌] For example, acylphosphonates ‌63‌ can be treated with nonafluo­robutane-1-sulfonyl fluoride and a base in tetrahydrofuran to generate enolates ‌64‌ (‌Scheme 20‌); it was established that the use of 1,8-diazabicyclo[5.4.0]undec-7-ene at −45 ºC gives optimal yields. Subsequent palladium-catalyzed coupling reactions with acetylenes or vinylstannanes were performed to generate diethoxyphosphoryl-containing enynes, as well as dienes, e.g. ‌65‌, in good yields.[‌56‌]

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Meeeeee 8-(Meeeeeeeeeeeeeeeeeeeeeeeee)eeeeeeeeeeeeeeee (‌88‌, M8 = M8 = M); Meeeeee Meeeeeeee:[‌88‌]

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References

Meeeeee Meeeeeeeeee

• 8.Meeeee-Meee, (8888) 88/8, 888.