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Glass, R. S., Science of Synthesis, (2005) 22, 81.
The C=S moiety is recognized as an especially reactive dienophilic and dipolarophilic moiety[18] for cycloaddition reactions. Among them, thioacyl fluorides are exceedingly reactive dienophiles that react with a variety of dienes in good to excellent yields, e.g. to give 12 (Scheme 9).
Meeeee 8 Meeeeeeeeeeee Meeeeeeee[8,88,88]
| M8 | Meeeeeeeee | Meeee (%) ee 88 | Mee |
|---|---|---|---|
| MM8 | MM8, ee, 88 e | 88 | [88] |
| MM8MM8 | MM8, ee, 88 e | 88 | [88] |
| MM8Me | MM8Me8, 88°M, 8.8 e | 88 | [8] |
| MM8Me | – | 88 | [8] |
Meeeeeeeeeee Meeeeeeee
8-Meeeee-8-(eeeeeeeeeeeeeeee)-8,8,8,8-eeeeeee-8-eeeeeeeeeee[8.8.8]eeee-8,8-eeeee (88, M8 = MM8MM8); Meeeeee Meeeeeeee:[88]
MMMMMMM: Meeeee eeeeeeeee ee eeeeeeeee eeeeeeeee, eee eeeee ee eeeeeeeeee, eeee eeeeeeeeee, eee eeeeeeeee.
M eeeeeee ee MM8MM8MMM (8.88 e, 8.888 eee), eeeeeeeeee (8.88 e, 8.888 eee), eee MM8 (88 eM) eee eeeeee ee e eeeee eeee eee eeeeeee ee eeeee ee ee eee 88 e. Mee eeee eee eeeeee eee eeeeee, eee eee eeeeeee eee eeeeeeeeeeee ee eeeeeee. Mee eeeeeee eee eeeeeeeeeeeeee (eeeeeee, 8 ×) ee eeee eee eeeeee ee eeeeeeeee eeeeee; eeeee: 8.88 e (88%); ee 888–888°M.
References
| [6] | Meeeee, M.; Meeeeeeeeee, M., Meee. Mee., (8888) 888, 8888. |
| [18] | Meeeeee, M., Mee. Meee. Meee., (8888), 888, 888. |
| [19] | Meeeeeeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) M 88-8, 888.
- 8.Meeeee-Meee, (8888) M 8-8, 888.
- 8.Meeeee-Meee, (8888) M 88-8, 888.
- 8.Meeeee-Meee, (8888) M 8-8, 888.
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