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Please login to access the full content or check if you have access via Variation 1: Modifications of the Classical Pinner Method (via Imidates)

DOI: 10.1055/sos-SD-022-00489

Ostrowska, K.; Kolasa, A.Science of Synthesis, (200522392.

Modifications of the classical Pinner reaction are:

(8) Mee eeeeeeee ee eeeeeee ee eeeeeee eee eeeeeeeee eeeeee (eee MeeeeeMeee, Mee. 8, e 888 eee Mee. 88/8, e 88), eeeee eeeeeee ee eee eeeeeeeee ee M-eeee-[‌88‌,‌88‌,‌88‌,‌88‌,‌888‌,‌888‌,‌888‌,‌888‌‌888‌,‌888‌‌888‌] ee M8,M8-eeeeeeeeeeeee eeeeeeee[‌88‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌] ee eeeeee eeeeeeee.[‌88‌,‌88‌,‌88‌,‌88‌,‌88‌,‌88‌,‌88‌,‌88‌,‌88‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌,‌888‌]

(8) Meeeeee eeeeee eee eeeeee eeeee ee eee eeeeeeeeeeee ee e eeee eeeee eeeeeeeeeee, eeee ee 8-eeeeeeeeeeeee-[‌88‌,‌888‌] ee 8-(8-eeeeeeeeeeee)eeeeee eeeeee[‌888‌] ee eeeeeee eee eeeeeeeeee ee eee eeeee eeeeeeee eee ee eeeeee eeeeee eeeeeeee ee eee eeeeeee eeeee.

(8) Meeeeee ee eee eeeeeeee eeeeeeeeee; eee eeeeeeee ee eeeeeeeee eeeee eeeeeeee eeeeeeeeee.[‌88‌,‌888‌‌888‌]

Me eeee eee-eeee eeeeeeee, eeeee eeeeeeee eee eee eeeeeeeee ee eeeeeeee eeee eeee eee eeeeeeeeee, ee ee eeeeeeeee eeee e eeeeeeeeeeeeee eeeeee ee eeeeeee ee eeee ee eee eeeee eeee ee eeeee eee eeeeeeeee ee eeeee eeeeee. Mee eeeeeeee ee eee eeeeee eeee eee eee eM ee eee eeeeeeee eeeeeeee eeeeeee eee eeee eeeeeee ee eeeeeee eeeeeeeeee. Me eee eeee eeeeeee[‌888‌,‌888‌,‌888‌] eeee eee eeeeeeee ee eeeeee ee eeeeeeee (e.e., 88, Meeeee 88), eeeee eeeeeee ee eee eeeeeeeee ee eeeeeeeeeee eeeeeeeeeeeee, ee eM eeeeeeeee; eeeeeeeeeeeeeee eeeeeeee (e.e., 88) eee eeeeee eeeeeeeeeee ee eeeeee eM eeeee eeeeeeeeeeeee eeeeeeee eee M8,M8-eeeeeeeeeeeee eeeeeeee (e.e., 88) eee eeeeee ee eeeee eM.

Meeeee 88 Meeeeeee ee Meeeee ee Meeeeeee[‌888‌]

Me eeeee ee eeeeeeee e eeee eM ee eee eeeeeeee eeeeeee, ee eeeeee ee eee eeeee (ee ee 8:8) ee eee eeeeeeee ee eeeeeeeeeeeee[‌88‌,‌888‌,‌888‌,‌888‌] ee ee eeeeeee eeeeeee eee eeeeeeee. Me eee eeeeeeee ee eeeeeeeee ee eeeee ee ee eeeeeee ee eeeee eee ee eeeeeee eeeeeee, eee eeeeeeee ee eeeeeeeee eeeeeeeee, eeeeee eeeeeeeee, Meeee-8, ee eeeeeeeeeeeee ee eeeeeeeee. Meee ee eeeeeeeeeee ee eeee eee eeeeeeeeee eeee ee eee eeeeeee eeeee ee eeee eeee ee eeee eM. Mee eeeeeeeeeeeeee ee eee Meeeee eeeeee ee eeee ee ee eeeeeeeeee eeee eee eeeeeeeee eeeeeeeeee eeeeee: eeeeeeeeee, eeeeee, eeeeee, eeeeeeeeeeee, eeeeeeeee eeeeee, eee eeeeeee (Meeee 8).

Meeee 8 Meeeeeee ee Meeeee ee Meeeeeee[‌88‌,‌88‌,‌88‌,‌888‌,‌888‌,‌888‌]

Meeee Meeeeee Meeeeeeeeeeee Meeeeeeeee Meeeeee Meeee (%) Mee
8 M8MMM8MM8MM8, (8.8 eeeee), eMeMM, 8°M eeee 88°M, 88e 88 [‌88‌]
8 8. M8MMM8MM(MMe)8, MeMM, 8°M, 8e8. 8M MeMM 88 [‌888‌]
8 eeeeee MeMM8, 88°M eeee 88°M ee 88°M, 88eee 88 [‌88‌]
8 8. MMM, Me8M, 8°M8. eeeeee 8-(eeeee­eeeeee)eeeeeeee, Me8M, 88°M, 88e 88 [‌888‌]
8 M8MMM8MM8MM8, MeMM, eeeeee, 8e 88e [‌88‌]
8 eeeeee eeeeeeeeeee, MeMM, ee, 88e 88 [‌888‌]

e Me8=8-MMM8M8.

Me eee eeeeeeeee Meeeee eeeeee, eee eeeee eeee ee eeeeeee eee eeeee eeeeeeee eeee eeeeeeeeee; eeeee eeeeeeeeee eee eeeeee ee eee eeeeeee eeeeeeeeeeeee ee eee eeeeeeee eeeeeeee, eeeeee eeeeeeee ee eeeeee. Meeee eee eeeeeeeeee ee eeee-eeeeeeeee eeeeeeee ee eeeeeeee eeee eeeeeee ee eeeeeeee-eeeeeeeeeee eeeee ee eee α-eeeeeeee eeee eee eeeeeeeeeeeee eeeeeee eeeee ee ee eeeeeeeee eeeee eeeeeeee eeeeeeeeee; eeeeeeeee eeeeeeeee ee eeeeeeeee[‌88‌,‌888‌‌888‌,‌888‌‌888‌] ee eeeeeeeee eeeeeeeee[‌888‌] eee eeeeeeeee eeee. Me eeeeeee ee eeeee eee eee eeeeeeeee ee eee eeeeeee eeeeeeeeeeeee 88 eeee eeeeeee 88 (Meeeee 88) eeee eeeeeeeee eeeeeeeee,[‌888‌] eeeee eeeeeee eeeeeeee eee eeeee ee Meeee 8.

Meeeee 88 Meeeeeeee ee ee Meeeeee eee ee Meeeeee ee Meeeeeee Meeee[‌888‌]

Meeee 8 Meeeeeeee ee Meeeeeee eee Meeeeeee ee Meeeeeee Meeee[‌888‌‌888‌,‌888‌]

Meeee Meeeeee Meeeeeeeee Meeeeee Meeee (%) Mee
8 8. MeMMe, MeMM, 8°M8. MMe, 888°M8. eeeeee M8MMM8MM8MM8, 888°M, 8.8e eeee ee, 88e 88 [‌888‌]
8 8. MeMMe, MeMM, ee, 88e8. MeMM, Meeee M+, eM 88. eee. MM8(e)/MeMM, MM8Me, eeeeee eeeeee, ee, 88e 88 [‌888‌]
8 8. MeMMe, MeMM, eM 8, ee, 88e8. MM8Me, MeMM, ee, 8e 8. 88% 8. 88% [‌888‌]
8 MeMMe, eeeeee M8MMM8MM8MM8, MeMM, eeeeee, 8e 88 [‌888‌]

Meeeeeeeeeee Meeeeeeeee

Meeeee 8-[(Meeeeeeeeeeeeeeeee)eeeeee]eeeeeeee (Meeee 8, Meeee 8):[‌888‌]

M eeee ee eee eeeeee eeeeeeeeeeeeee eeeeeeeeeeeee (88.8e, 888eeee) ee MMM (888eM) ee 8°M eee eeeeeee eeee Me8M (88.8eM, 888eeee) eeeee M8. Mee eeeeeeeee eeeeeeeeee eee eeeeeee ee ee eee 8e eee eeee eeeeeeee. Mee eeeeee eeee ee Me8MMMe eee eeeeee eeee MMM (88eM). Mee eeeeeeee eeeeeeeee eeee eeeeeeeeeee eeee e eeeee eeeeee eeeee M8 eee eeeeeee eeee eeeeee 8-(eeeeeeeeeee)eeeeeeee (888eeee) eee Me8M (88.8eM, 888eeee). Mee eeeeeee eee eeeeee ee 88°M eee 88e. Meeee eeeeeee, eee eeeeeee eee eeeeeeeeeee eeeeeee MeMMe eee M8M. Mee eeeeeee eeeee eee eeeeee eeee M8M eee eeeee eee eeeee (MeMM8). Meeeeeee eeeeeeee eeee eeeeeee ee eeeee. Mee eeeeeeeee eeeeeee: eeeee: 88.8e (88%); MM ν̃eee: 8888, 88888888, 88888888, 8888, 8888, 8888, 8888, 8888, 8888, 8888, 888ee8.

8,8-Meeeeee-8-eeeee-M-eeee-eeee-8-eeeeeeeeeeeee Meeeeeeeeeeee (Meeee 8, Meeee 8):[‌888‌]

Mee 8,8,8-eee-M-eeeeee-8,8-eeeeeee-8-eeeee-M-eeee-eeee-8-eeeeeeeeeeee (8e, 8.88eeee) eee eeeeeeeee ee eee MeMM (8eM) ee ee eee 8M MeMMe ee MeMM eee eeeee eeeeeeee eeeee eee eeeeeee eeeeeeee eeeeeeeeeee eeeee (eM ~8). Mee eeeeeee eee eeeeeee ee ee eee 88e ee eeeee eee eee eeee ee eeeee eee eee eeeeeeeeeeeeeee ee eeeee. Meeee eeeeeee eee eeeee ee e eeeeeeeeeeee eee 88e, eee eeeeeeee eeee eeeeeeee eee; eeeee: 8.88e (88%).

Me e eeeeeeeeee ee eeeeee 8,8-eeeeeee-8-eeeee-M-eeee-eeee-8-eeeeeeeeeee (888ee, 8.88eeee) ee eee MeMM (8eM) eee eeeee MM8Me (88ee, 8.88eeee). Mee eeeeeee eee eeee eeeeeee ee ee eee 8e. Mee eeeeeeeeeeee eeee eeeeeeeeeee eeeee eee eeee eeeeeeee eee. Meeeeeeeeeeee ee eee eeeeee eeeeee eeeeeeee e eeeeeee eeee; eeeee: 888ee (88%); [α]M 88 (e 8.88, M8M).