You are using Science Of Synthesis as a Guest.
Please login to access the full content or check if you have access via23.10.6.1.1 Method 1: Thermolysis of 1,2,3-Benzotriazin-4(3H)-ones
Please login to access the full content or check if you have access via
DOI:
10.1055/sos-SD-023-00342
Kollenz, G., Science of Synthesis, (2006) 23, 372.
Thermal decomposition of 3-(benzylideneamino)-1,2,3-benzotriazin-4(3H)-ones 100 is a convenient procedure to obtain 2-arylquinazolin-4(3H)-ones 102 in yields of 56–71% (Scheme 28).[53] Elimination of nitrogen gives 6-(oxomethylene)cyclohexa-2,4-dien-1-imine (101), which adds to the corresponding nitrile by a hetero-Diels–Alder process (Scheme 28). This transient imidoylketene 101 is also capable of undergoing a cyclocondensation reaction with α-amino acids to afford 1,4-benzodiazepine-2,5-diones 103 in moderate yields.[54]
Meeeee 88 Meeeeeeeeeeeee ee Meeeeeeeeee ee 8,8,8-Meeeeeeeeeee-8(8M)-eeee[88,88]
References
[53] | Meeeeeee, M. M.; Meeeeee, M. M.; Meeeeeeeee, M., Meeeeeeee, (8888), 888. |
[54] | Meeee, M.; Meeeee, M.; Meeeeee, M.; Meeeeee, M., Meeeeeeeee. Meeeee., (8888) 8, 888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) M 8e, 888.
- 8.Meeeee-Meee, (8888) M 8e8, 88.