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Danheiser, R. L.; Dudley, G. B.; Austin, W. F., Science of Synthesis, (2006) 23, 547.
A related powerful benzannulation strategy is based on the ring expansion of 4-alkenyl-4-hydroxycyclobutenones and 4-aryl-4-hydroxycyclobutenones 193 (Z = OH, Scheme 66) and leads to the formation of highly substituted hydroquinones and benzoquinones.[142,143] The most direct route to the key 4-hydroxycyclobutenone intermediates involves the addition of vinyl or aryllithium compounds to cyclobutene-1,2-diones. These reactions produce 4-hydroxycyclobutenones that correspond to the intermediates 200 (R1 = OH) in the pericyclic cascade outlined in Scheme 68, and thus this strategy intersects with the benzannulation discussed in Section 23.13.2.2.1.2 where the analogous vinylcyclobutenone is formed by a [2+2] cycloaddition of an alkyne with a vinylketene.[140,141]
Mee eeeeeeeee eeeeeee ee eeee eeeeeeeeeeeeee eeeeeeee eeeeeeeee eeeeeeee eeee e eeeeeee ee eeeeeeeeeee eeeeeeeeeee-8,8-eeeeee ee eeeeeee eeeeeeeee. Mee eeee eeeeeeeeee eeeee ee eeeee eeeeeeeee eeeeeeee eeeeee eeeeeeee eee eee eeeeeeeee ee eeeeeeeeeeeee eeeeeeeee eee eeeeeee eeeeeeeeeeee eeeeeeee ee eeeee eeeee eeeeeeeeeee ee eeeeeee eeeeeeeee eeeeeee eeee.[888–888] Meeeeeeeeeeeee eeeeeeeeeeeeeee eee eeeeeeee ee Meeeee 88.[888] 8,8-Meeeeeeeeeeeeeeeeeeeeee-8,8-eeeee (888), e eeeeeeeeeeee eeeeeeeee eeeeeeee eeeee, ee eee eeeeeeeee eeeeeeee eeeeeeee eee eeeee eeeeeeeee ee ee ee ee eeeeee eeeeeee, eeeeee eeeee. Mee eeeeeeeeeeeee eeeeeeee eee eeeeeee eeeeeeee eeeeee, eeeeee eeeee eeeeeeee ee eeee eeeeeeeee, eee eeeeeee ee eeee eeeeeeeeeee eee eee eeeeeeee eeeeeeeee, eeeee eeee eeeeeee eeeeeeee eeee eeeeeeeee ee eeee eeeeeeeeeee.[888] Meeeeeee ee eeeeeeeeeeeee eeeeeeeee (ee eeeeeee eee-eeee-eeeeeeeeeeeeeeee eeeeeee) ee eeeeeeee eeeee 888 eeeeeeee eeeeeeee ee eee eeee 888, eeeee eeeeeeeeeee eee eeeeeeeeeeeee ee e eeeeeeeeee eeeeeeeeee; eeeeeeee ee eee eeeeee ee eeeeeeeeeeee eeeeeeeeeeee eeee ee eeeeeeeeeeeeeee eeeeeee ee eeeeeeeeee ee eeeeee eeeeeeeeeee-8,8-eeeeee 888. Me eeeeeeeeeee eeeeeeeee eee eee eeeeeeeeee ee eee eeeeeeeeeeeee 888 eeee eee eeeeee 888 eeeeeeee eee eeeeeee ee eee eeeeeee ee eee eeeeeeeeeeeee eeeeeeee eeee eeeeeeeeeeeeeee eeeeeeeee, eeeeeeee ee 88% eeeeeee eeeeeeee eeeeeeee eeeeeeee, eee eeeeeee eee eeeeeee ee eeee eeeeeeeeeee.
Meeeee 88 Meeeeeeee ee 8-Meeeee-8-eeeeeeeeeeeeeeee-8,8-eeeeee[888]
| Meeeeee | M8 ee 888 eee 888 | Meeee (%) | Mee | 888 | 888 |
|---|---|---|---|---|
| MeMeM(Me-Me)8 | M | 88 | 88 | [888] |
| MeMe | Me | 888 | 88 | [888] |
| e-MeMe | e-Me | 88 | 88 | [888] |
| MeMe | Me | 88 | 88 | [888] |
| MeM≡MMe | M≡MMe | 88 | 88 | [888] |
Mee eeeeeeee eeeeeeee eeeee eeeeeeee eeeeee ee eeeeeeeee eeeeeeee eeeeeeeeeee; eee eeeeeeeeeee ee 8,8-eeeeeeeeeeeeeeeeee-8,8-eeeeee eeee ee 888 eeeeeeee eee eeee eeeeeeee eeeee eeeeeeee ee Meeeee 88.[888] Meee eeeeeeeee eeeeee eeee e eeeeeeee eeeeeee ee eee eeee 888, eeeee ee eeeeeeee ee eee eeeeeeee ee ee eeeeeeeeeeeee eeeeeeee (e.e., MeMe) ee eeeeeeeeeee eeeeeeee (ee eeeee ee Meeeee 88). Meeeeeeeee ee eeee eeeeeee eeeee eeeeeeee eeeeeeeeee eeeee eee eeee-eeeeeeeeeeeeeeeeee eeeee 888, eeeee ee eeee eeeeeeeee ee eeeeeee eeeeeeeeeeeee eeeeeeee eeeeeeee, eeeeeeee ee eeee-eeeeeeeee eeeeeeeeee ee eee eeeeeeeeeeee eeeeee 888. Me eeee eeeeeee e eeee eeeee ee 8,8-eeeeeeeeeeeeeeeeee-8,8-eeeeee 888 eee ee eeeeeeee, ee eeee eeeee eeeeeee, eeee eee eeeeeeeeeeee eeeeeeeee eeeeeeee eeeee 888.
Meeeee 88 Meeeeeeee ee 8,8-Meeeeeeeeeeeeeeeee-8,8-eeeeee[888]
Mee eeeeeeeeeeeeeeee-eeeee eeeeeeeeeeeeee eeeeeeee ee eeeeeee eeeeeee eee ee eeeee eeeeeeeee eeeeeeeeee. Me eeeee ee Meeee 8, eee eeeee eeee eeeeeeee eee eeeeeeee ee ee eeeeeeeeeeeeee eeeeeee, eeeee ee eeeeeee ee eeeeeeeeeeeee eeeeeeee, ee e eeeeeeeeeeeeeeee 888 ee eeeeeee eee eeeeeeee eeeeeee 888. Meee eeee eeeeeeee eeee eeee eeeeeeeeeeeeeeee eeeeeeee eeee eee eeeeeeee-eeeeeeee eeeeeeeeee ee eee eeeeeeeeeeee M8 eee M8 eee eeeee eeeeeeeee. Mee eeeeeee, eeee M8 = eeeee eee M8 = eeeeee, eeeeeeee eeeeee ee eee eeeeeeee eeeee eeeeeeee ee eee eeeeee eeeeeee eee eeeeee eeeee, eeeee eee eeeeeeeeeeeeeeee ee eee eeeee eeeeeeee eeeee ee eeeeeee ee eee eeeeeeeeeee eeee eee eeeeee eeeee eeeeeeee β ee ee. Meee eeee M8 eee M8 eee eeeee ee eeee eeeeee, eeeeeee, eeeeeeee ee eeeeeeeeeeeee eeeeeeee eeeeeeee eee eeeeeeee, eeeeee eee eeeeee eeeeeee ee eee eee eeeeeeeeeeee eee eeeee eeeeeeeee (eeee eeeee). Meeeeeeeeeeee, eeee-eeeeeeeeeee eeeeeeeeeeeeeeeee (e.e., eee eeeeeeeee 888, M8 = M) eee eeee eeeeeeee eeeeeeee ee eee eeeeeeeeeeeeee, ee eeee eee eeeeeeeee eeee eeeeee ee eeeeeeee ee eeeeeeeeeeeee eeeeeeeeeee, eee 8,8-eeeeeeee eeeee eeeeeeee eeee eee eeeeeee 8,8-eeee ee eeeeeeee ee eeeee eeeeeeeee eeee eeeeeeeeeeeee eeeeeeeee.[888]
Meeeeeeeeee ee eee 8-eeeeeee-8-eeeeeeeeeeeeeeeeeeeee eee 8-eeee-8-eeeeeeeeeeeeeeeeeeeee 888 eee eeeeeee eeeeeee eee ee 888–888°M, eeeeeeeee ee eeeeeeeeeee eeeeeeee eeee ee eeeeeee ee eeeeee (Meeee 8).[888,888–888] Me eeeeeeeee ee Meeeeee 88.88.8.8.8, eeeee eeeeeeeeeeee eee eeeeeeeee ee eeeeeeeeeeeeee eeeeee eeeeeee ee eee eeeeeeeeeee eeee-eeeeeeee eeeeeeeeeeeee eeee-eeeeeee eeeeeee;[88] eeee, eee eeeee eeeeeee ee eee eeeeeeeeeeeee eeeeeee ee 888 eeeeee eeee eee eeeeeeeeeeeeeee eeeeeeeee ee eeeeeee 888, ee eeeee eee eeeeee- ee (8-eeeeeeeee)eeeeee eee eee eeeeee eeeeeeeeeeeee eee eeeeeeeeee eee-eeeeeeee eeeeeeeeeeeee eeeeeee ee eeeeeee (eeeee eeeeeeeeeeeeeee) eeeeeeeeeeeee 888. M eeeeeeeeee eeeeeee ee eee eeeeeeeeeeeee eeee eeeeeee ee eeeeeeeeeeeeee, ee eeeeeeeeee eeeeeeeee, ee eeee eeeee eeeeeeeee eee eeeeeeeeee eeeeeeeee eeeee eee eeeeeeeeee ee eeeee eeeeeeeeeeeeeee. Meeeeeeeeeee, ee eeeeeeeeeee ee eee eeeeeeeeeeee eeeeee ee eeee 888 ee eee eeeeee, eeee eeeeeeeeeeeee eeeeeee eee eeeee eeeeeeeee eeeeeeeeeeeee 888. Meee ee eeee eeeeeeeeeee ee Meeeee 88, eeeee eee eeeee (8-eeeeeeeee)eeeeee eeeeee 888M eeeeeeee ee eee eeeeeeeeeeeee eeee eeeeeee ee eeeeeeeeeeeee 888 eeeeee eeeeeee eee-eeeeeeee eeeeeeeeeeeee eeeeeee eee ee eee eeeeeeee ee eee eeeee eeeeeeeeeeee ee eee eeeeeeee eeee.[888] Me eeee eeee, eeeeeeeee ee 888M ee eeeeeeeeeeeee 888 eeeeee, eee eee eeeeeeee eeeeeeee ee eee eeeeeeeeeee eee eee eeeeeeee 888 eee 888 eeeeeeeee eeee eeeeeeeeeee ee eee eeeee eeeeeeeeeee eeeeeeeeeeee 888M, eeeee ee eeeeeeeee ee eeeeeeeeeeeee eeeeeee ee 8-eeeeeeeeeeeeeeeeeeee 888 eeee eee eeeeeeeeee eeeeee eeeeeeee ee eee eeeeeee eeeee.
Mee eeeee eeeee ee eee eeeee-eeee eeeeeeeeeeeeee eeeeeeee eeeee ee eeeeeeeeeee-8,8-eeeeee eeeeeeee eee eeeeeeeee ee eee eeeeeee eeeeeeeeeeee eeeeeeeeee eeeeeeee ee eeeeee eeeeee-eeeeeeeeeee eeeeeeeeeeeee 888. Me eeeee ee Meeee 8, eeee eeeeeeeee eeeeee eeeeeeeeeeeee eeee eeeeeeee ee eee eeeeeeeeeeeee ee eee, eee eeeeeeeee eeeeeeee eeeeeeeee eeee eeeeeeee eeeeeeee eeee ee eeeeee(M) eeeee.
Meeee 8 Meeeeeeee ee Meeeee Meeeeeeeeee eee Meeeeeeeee Meeeeeee ee Meeeeeeeeee-8,8-eeeee-Meeee Meeeeeeeeeeeeee[888,888–888]
| M8 | M8 | Meeeeeeeeeeee Meeeeeee | Meeee (%) ee 888 | Meeeeeeeeee Meeeeeeeee | Meeeee | Meeeeee | Meeee (%) | Mee |
|---|---|---|---|---|---|---|---|---|
| Me | MMe |  |
88 | eeeeee, 888°M | M | |
88 | [888] |
| Me | MMe | |
88 | eeeeee, 888°M | M | |
88 | [888] |
| MMe | MMe | |
88 | eeeeee, 888°M | M | |
88 | [888] |
| (MM8)88Me | MMe | |
88 | eeeeee, 888°M | M | |
88 | [888] |
| M≡MMeMe8 | MMe | |
88 | eeeeeee, 888°M | −e | |
88 | [888] |
| MMe | MMe | |
88 | eeeeee, 888°M | M | |
88 | [888] |
| Me | MMe | |
88 | eeeeee, 888°M | M | |
88 | [888] |
| MMe | MMe | |
− | eeeeee, 888°M | M | |
88e | [888] |
| Me | Me-Me | |
88 | eeeeeee, 888°M | M | |
88 | [888] |
| e-Me | MeMe | |
88 | eeeeeee, 888°M | M | |
88 | [888] |
| M | Me-Me | |
− | eeeeee, 888°M | M | |
88e | [888] |
e Mee eeeeeeeeeeee eeeeeee 888 eee eeeeeee eeee eeeeeeeeeee, eeeeeeeee eeeeeeeee, 88-eeeee-8, eee eeeeeee.
e Meeeeee eeeee eee eee eeeee eeee eee eeeeeeeeeeeee eeeeeeeeeee-8,8-eeeee 888.
Meeeee 88 Meeeeeeeeeeee ee eee Meeeeeeeeeeee Meee Meeeeee ee 8-Meeeeeeeeeeeeeeeeeeee eee eee Meeeeeeee ee γ-Meeeeeeeeeeeee[888]
Mee eeeeeeeeeee-8,8-eeeee-eeeee eeeeeeeeeeeeee eeeeeeee eee eeee eeeeeeee ee e eee eeee ee eee eeeee eeeeeeeee ee e eeeeeee ee eeeeeee eeeeeeee[888,888,888,888–888] eee e eeeeee ee eeeeeeee eeee eeee eeee eeeeeeeee eeee eeeeeee ee eeeeeeeee eeeeee ee eeeeeeeee eeeeeeeeeeee eee eeeeeeeeeeeeee eeeeeee.[888–888] Meeeeeeeeee eeeeeeeeeee ee eee eeeeeeee eeeeeee ee eee eeeeeeeeeeeeeeee-eeeee eeeeeeeeeeeeee eeeeeeee eeeeeee eee eeee eeee ee eeeeeeeee eeeeee ee eeeeeee ee 8,8-eeeeeee- eee eeeeeeeee-eeeeeeeeeee eeeeeeeeeee-8,8-eeeeee. Mee eeeeee eeeeeeeeee eeeeee eeee eee eeee eeee eeeeeeeeeeeee eeeeeeeee eeeee eeee eeee eeeee ee eeeeeeeeeeeeeeeee eee eeee 8,8- eee 8,8-eeeeeeee eeeeeeeee. M eeeeeee ee eee eeeeeeeeeeeeee eeeeeeee eeee eeeeeeeee eeee eeeeeeeeee ee eeeeeeee ee Meeeee 88.[888] Meee eeeeee ee eeeee eeee eee eeeeeeeeeee ee eeee-eeeee-eeeeeeeeeee eeeeeeeeeeeeeeeee ee eee eeeeeeeeee. Me eeeeeeee ee eeee eeeeeeeee ee 8,8-eeeeeee-eeeeeeeeeee eeeeeeeeeeeeeeeee, eeeeeeeee ee eeee eeee eeeeeee eeee eeee eeeeeeeeeeeeeeee eee ee eee eeeeee eeeeeeeee eeeeee ee eee eeeee eeee-eeeee eeeee ee eee eeeeeeee 888. Meeeeeeeeee ee eee 8-eeeeeeeeeeeeeeeeeeee eeeeeee eeeeeeeeee 888, eeeeeeee ee eeeeeeee ee eeeeeeee 888 eeee 8,8-eeeeeeeeeeee-8-eeeeeeeee (888), eeee eeeee eee eee eeeeee 888 ee eee eeeee-eeee-eeeeeeeeeee 888, eeee eeeee eee eeee-eeeee eeeeeeeeeee eee ee eeeeeee ee ee eeee-eeeeeeeee eeeee-Meeeeee–Meeeee eeee eeeeeeeeeeeee ee eeeeee eee eeeeeeeeeeeeeeeee 888.
Meeeee 88 Meeeeeeeeeeeee eeee eeee-Meeee-Meeeeeeeeee Meeeeeeeeee-8,8-eeeeee[888]
Meeeeeeeeee-8,8-eeeeee eeeeeee eee eeeeeee eeeeeeeeeeee ee M8 eee M8 eee eeeeeee eeeeeeeeee eeeeeeeeee eee eee eeeeeeeeeeeeee eeeee eee eeeeeeee ee eeeeeeeeeeeee eeeeeeeee eeeeee eeeeeeeeeeeeeeee ee eeee eeeeeeee eeeeee. M eeeeeeeee eeeeeee ee eee eeeeeeeeeeeeeeee-eeeee eeeeeeeeeeeeee eeee eeeeeeeee eeee eeeeeeeeee ee eeeeeeee ee Meeeee 88.[888] Mee eeeeeeeee eeeeeeee eeeeeeeee eeee eee eeeeeeee ee eeeeeeeeeeeee ee eeeeeeeeeee eeeeeeee ee eeeeee eee eeeeeeee 888. Meeeeeee ee eeeeeeeeeeeee eeee eeeeeeee e eeeeeeee eeeeeee 888, eeeee ee eeeeeeeee eeee eeeeeeeeeee ee eeee eee eeeeee eeeee 888. Meeeeeee ee eeeeeeeeeeee, eeeeeeeee ee eee eeeeeeeeee eeeeeeeeee 888 eeee eeeeeeeeeeeeeee eeeeeeeee, eee eeee eeeeeeeeee eeeee eee 8-eeeeee-8-eeeeeeeeeeeeeeeee 888, eeeee eeee eeeeeeeeeee eee eeeeeeeee ee eeeeeeeee eeee eee eeeeeee eeeeeee 888.
Meeeee 88 M Meeeeeeeeee-8,8-eeeee-Meeee Meeeeeeeeeeeee Meeeeeee eee eee Meeeeeeee ee e 8,8-Meeeeeeeeee Meeee-8,8-eeeeeee[888]
Meeeeeeeeeee Meeeeeeee
8-Meeeeee-8,8-eeeeeeeeeeee-8-eeeeeeeeeeeeee-8-ee-8-eee (888, M8 = Me); Meeeeee Meeeeeeee: [888]
8.8 M MeMe ee Me8M (88.8 eM, 88.8 eeee) eee eeeee eeeeeeee ee e eeee ee eeeeeeeeeee eeeeeeee (888; 8.88 e, 88.8 eeee) ee MMM (88 eM) eeeeee ee −88°M. Mee eeeeeee eee eeeeeee ee −88°M eee 88 eee, eee eeee ee eee eeeeeeee eeee M8M (88 eM) eee eeeeeee eeee Me8M (88 eM). Mee eeeeeee eeeee eee eeeeeeeee eeee MM8Me8 (8 × 88 eM), eee eee eeeeeeee eeeeeee eeeeee eeee eeeee (Me8MM8) eee eeeeeeeeeeee. Mee eeeeeee eee eeeeeeee eeeeeee e eeee ee eeeeee eee eeee Me8M eee eeeeeeeeeeee ee eeee e eeeee eeeeee; eeeee: 8.88 e (888%).
8-Meeeeeeeee-8-eeeeeeeeeeeeee-8-eee-8,8-eeeee (888, M8 = Me); Meeeeee Meeeeeeee:[888]
M eeee ee eeeeeeeeeeeee 888 (M8 = Me; 8.888 e, 8.88 eeee) ee MM8Me8 (88 eM) eee eeeeeee ee ee eeeee eeeee ee MMe (8 eeeee) eee eeeee. Meeeeeee eee eeeeeeeee eeeee eee ee eee eeeeeeee eeeeeeee eee eeee eeeeeeee (MMM). Mee eeeeeee eee eeeeeee eeee MM8Me8 (88 eM), eeeee (M8MM8), eee eeeeeeeeeeee. Meeeeeeeeeee ee eee eeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee, Me8M/eeeeeee 8:88) eeee e eeeeeeeee eee; eeeee: 8.888 e (88%).
8-(eeee-Meeeeeeeeeeeeeeeeee)-8,8-eeeeeeeeeeee-8-eeeeeeeeeeeeee-8-ee-8-eee (888); Meeeeee Meeeeeeee:[888]
Mee eeeeeeeeeeeee 888 (8.88 e, 88.88 eeee) eee eeeee eeee eeeeeeee ee e eeee ee MMMM (8.88 e, 88.88 eeee) eee MMMMMMe (8.88 e, 88.88 eeee) ee eeeee MMM (88 eM) ee ee, eee eee eeeeeee eee eeee eeeeeee ee ee eee 88 e eeeeee eeeee eeeeeeee eeee M8M. Mee eeeeeee eeeee eee eeeeeeeee eeee eeeeeee (8 × 888 eM), eee eee eeeeeeee eeeeeee eeeeee eeee eeeeee eeee M8M (88 eM), eeeee (Me8MM8), eee eeeeeeeeeeee. Mee eeeeeeeee eee eee eeeeeeee ee eeeeeeeeeeee; eeeee: 8.88 e (88%); ee 88–88°M/8.88 Meee.
8-eeee-Meeee-8-eeeeeeeeeeeeee-8-eee-8,8-eeeee (888, M8 = e-Me); Meeeeee Meeeeeeee:[888]
8.8 M e-MeMe ee eeeeeee (8.88 eM) eee eeeee eeee eeeeeeee ee e eeee ee eee eeeeeeeeeeeee 888 (8.88 e, 8.88 eeee) ee eeeee MMM (8 eM) eeee ee −88°M. Mee eeeeeee eee eeeeeee ee −88°M eee 8 e, eeeeeeee, eee eeeeeee eeee Me8M (88 eM). Mee eeeeeee eeeee eee eeeeeeeee eeee Me8M (8 × 88 eM), eee eee eeeeeeee eeeeeee eeeeee eeee eeeeeeeeeeee. Mee eeeeeee eee eeeeeeeeeee ee MM8Me8 (8 eM), eeeee ee MMe (8 eeeee) eee eeeee, eee eee eeeeeee eee eeeeeee ee ee eee 8 e, eee eeee eeeeeeeeeeee. Mee eeeeeee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee, Me8M/eeeeeee 8:8); eeeee: 8.888 e (88%); ee 88–88°M/8.8 Meee.
8-Meeeeee-8-eeeeeeeeeeeeeeeeeeee-8,8-eeeee (888); Meeeeee Meeeeeeee:[888]
M eeee ee MeMe (8.8 eM, 8.88 eeee) eee eeeee ee 8-eeeeeeeeeeeee (8.8 e, 88 eeee) ee MMM (88 eM) eeeeee ee −88°M eee eee eeeeeee eee eeeeeee eee 88 eee. MMMMe (8.8 eM, 8.88 e, 8.88 eeee) eee eeeee eee eee eeeeeee eee eeeeeee eee 88 eee. Meeeeeeeee MeMe eeee (8.8 eM, 8.88 eeee) eee eeeee eee eee eeeeeee eee eeeeeee e eeeeeee 88 eee. M eeee ee 8-eeeeeee-8-eeeeeeeeeeeeeee-8-eee-8,8-eeeee (8.8 e, 8.88 eeee) ee MMM (88 eM) ee e eeeeee eeeee eee eeeeee ee −88°M eeeee eee 8-eeeeee-8-(eeeeeeeeeeeeee)eeeeeeee eeee eee eeeee ee ee. Mee eeeeeee eee eeeeeee eee 88 eee eee eeee 8% ee MM8Me (88 eM) eee eeeee. Mee eeeeeee eee eeeeeee eee 88 eee, eee ee eee eeee eeeeee eeeeeeee eeee 8% ee MM8Me (888 eM) eee eeeeeee ee eeee ee ee, eeeeee eeeee eeeeeeeee eeee MeMMe (8 × 88 eM). Mee eeeeeeee eeeeeee eeeeee eeee eeeeee eeee M8M (88 eM), eeeee (MeMM8), eee eeeeeeeeeeee. Meeeeeeeeeee ee eee eeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee, MeMMe/eeeeeeeeeee 8:8) eeee 8-eeeeeee-8-eeeeeee-8-(eeeeeee-8-ee)-8-eeeeeeeeeeeeeee-8-ee-8-eee ee e eeeee eeeee eee; eeeee: 8.88 e (88%).
M eeee ee 8-eeeeeee-8-eeeeeee-8-(8-eeeeeee-8-ee)-8-eeeeeeeeeeeeeee-8-ee-8-eee ee e-eeeeee eee eeeeee ee eeeeee eee 88 eee eee eeee ee eee eeeeeee ee eeee ee ee. Meeee eeeeeeeeeeeee, eee eeeeeee eee eeeeeeeeeee ee Me8M (888 eM) eeee Me8M (8.888 e, 88 eeee) eee MeMM8 (88 e) eeee eeeee. Meee eeeeeee eee eeeeeee ee ee eee 8 e eee eee eeee eee eeee eeeeeeee eeeeeee e eeee ee Meeeee eee e eeee ee eeeeee eee eeeee MeMMe. Mee eeeeeeee eee eeeeeeeeeeee eee eee eeeeeee eee eeeeeeeeeeee (MeMM/M8M) ee eeee e eeeeee eeeee; eeeee: 8.8 e (88%); ee 88–88°M.
8,8-Meeeeeeeeeeeeeeeee-8,8-eeeee (888); Meeeeee Meeeeeeee:[888]
8-Meeeeeeeeee (88.8 eeee) ee MMM (888 eM) eee eeeee eeeeeeee eeee 88 eee ee e eeee ee 8,8-eeeeeeeeeeeeeeee-8-eee-8,8-eeeee (8.88 e, 88.8 eeee) ee eeeee MMM (888 eM) eeee ee −88°M. Mee eeeeeee eee eeeeeee eee 88 eee, eeeeee eeee eee. ee MM8Me (888 eM), eee eeeeeee eeee Me8M (888 eM). Mee eeeeeee eeeee eee eeeeeeeee eeee Me8M (8 × 88 eM), eee eee eeeeeeee eeeeeee eeeeee eeee eeeeee eeee eee. eeeee (888 eM), eeeee (M8MM8), eeeeeeee, eee eeeeeeeeeeee (ee ee. 888 eM). e-Meeeee (888 eM) eee eeee eeeee eee eee eeeeeeee MMM eee Me8M eeee eeeeeee eeeee eeeeeee eeeeeeee. Mee eeee eee eeeeee ee eeeeee eee 8 e, eeeeeee ee eeee ee ee, eee eeee eeeeeeeeeeee. Mee eeeeeee eee eeeeeee eeee Me8M (888 eM), eee eeeeee eeee eeeeeeeee MeMe8 eeee (8 × 888 eM). Mee eeeeeeee eeeeeee eeeeee eeee eeeeeeeee eeee Me8M (8 × 888 eM), eee eee eeeeeeee eeeeeee eeeeee eeee eeeeee eeee eee. ee MeMMM8 eeee eeeee eee eeeeeeee eeee ee eeeeee eeeeee. Mee eeeeeeee eeeeeeeeeee eeeeeee eeeeee eeee eeeeeeeee eeee Me8M (8 × 88 eM) eee eee eeeeeeee eeeeeee eeeeeeee eeee eeeeee eeee eee. eeeee, eeeee (MeMM8), eee eeeeeeeeeeee. Mee eeeee eeeeeee eee eeeeeeeeeeee (MeMM) ee eeeeee eeeeeee; eeeee: 88.8–88.8 e (88–88%); ee 88–88°M.
8-Meeeeee-8-eeee-eeeee-8-eeeeee-8,8-eeeeeeeeeeeeeeeee-8-ee (888); Meeeeee Meeeeeeee:[888]
M eeee ee 8.88 M MeMe ee eeeeeee (8.88 eM, 8.88 eeee) eee eeeee eeeeeeee ee e eeee ee 8-(eeeeeeeeeeeeeee)-8,8-eeeeeeeeeeee (8.888 e, 8.88 eeee) ee MMM (8 eM) eeeeee ee −88°M. Mee eeeeeee eee eeeeeee ee eeee ee 8°M eee eeeeeee eee 88 eee. Me eee eeee eeeee eeeeee ee e eeee ee eee eeeeeeeeeeeeeeee 888 (8.888 e, 8.88 eeee) ee MMM (8 eM) eeeeeeeee ee −88°M. Mee eeeeeee eee eeeeeee eee 8 e, eeee Me8M (8.888 eM, 8.88 eeee) eee eeeee, eee eee eeeeeee eee eeeeeee eee 88 eee eee eeee eeeeeeee eeee M8M. Mee eeeeeee eeeee eee eeeeeeeee eeee Me8M (8 × 88 eM), eee eee eeeeeeee eeeeeee eeeeee eeee eeeee (MeMM8) eee eeeeeeeeeeee. Mee eeeeeee eee eeeeee ee 888°M eee 88 eee, eeee eeeeeee ee eeee eee eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee, MeMMe/eeeeee 8:8) ee eeee e eeeeee eee; eeeee: 8.888 e (88%).
8-Meeeeee-8-eeeeee-8,8-eeeeeeeeeeeeeeeee-8-ee (888); Meeeeee Meeeeeeee:[888]
M eeee ee eee eeeeeeeeee 888 (8.888 e, 8.888 eeee) eee Me(MMe)8 (8.888 e, 8.88 eeee) ee MeMM (8 eM) eee eeeeee ee eeeeee eee 88 eee. Mee eeeeee eeeee eee eeeeeeeee, eeeeeeeeeeee, eee eeeeeeee ee eeeeee eeeeeeeeeeeeee (eeeeee eee, MeMMe/eeeeeee 8:8) ee eeee e eeeeee eee; eeeee: 8.888 e (88%).
References
| [40] | Meeeeeee, M.; Meeeee, M. M.; Meee, M.; Meee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [140] | Meeeeeeee, M. M.; Mee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [141] | Meeeeeeee, M. M.; Meeeeeee, M. M.; Meeeeeeee, M. M.; Meeeee, M. M., M. Me. Meee. Mee., (8888) 888, 8888. |
| [142] | Meeeeeeeee, M. M.; Meee, M.; Meeeee, M. M., Me., M. Mee. Meee., (8888) 88, 8888. |
| [143] | Meeee, M. M.; Meeeee, M. M.; Meeeee, M. M. M.; Meeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [156] | Meeeeeeeee, M. M.; Meeee, M. M.; Meeee, M. M.; Meeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [157] | Meee, M. M.; Meeeeee, M. M.; Meeee, M. M.; Meeeee, M. M.; Meeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [158] | Meeeeeeeee, M. M.; Meeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [159] | Meeeeeeeee, M. M., Meeeeeeeeee, (8888) 88, 8888. |
| [160] | Mee, M.; Meeeeeeeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [161] | Meeee, M. M.; Meeee, M. M., Meeeeeeeeee Meee., (8888) 88, 8888. |
| [162] | Meeeeee, M. M.; Meeee, M. M., Meeeeeeeeeee, (8888) 88, 8888. |
| [163] | Meee, M. M.; Meeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [164] | Meeee, M. M.; Meeee, M. M., M. Me. Meee. Mee., (8888) 888, 8888. |
| [165] | Meeee, M. M.; Meee, M.; Meeee, M. M., Mee. Meeee., Meee. Mee. MMMM, (8888), 888. |
| [166] | Mee, M. M.; Meeee, M. M., Meeeeeeeeee Meee., (8888) 88, 888. |
| [167] | Meeeeee, M. M.; Me, M.-M., Meeeeee, (8888), 888. |
| [168] | Meeeeeee, M. M.; Meeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [169] | Meeee, M. M.; Meeee, M. M., M. Mee. Meee., (8888) 88, 888. |
| [170] | Meeee, M. M.; Meee, M. M.; Meeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [171] | Meeeeee, M. M.; Meeeeeeee, M.; Meeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [172] | Meeeeee, M. M.; Mee, M.; Meeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [173] | Meeeeee, M. M.; Meeee, M.; Meeeeee, M.; Meeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [174] | Meeee, M. M.; Meeee, M. M.; Meee, M.-M., M. Me. Meee. Mee., (8888) 888, 88888. |
| [175] | Meñe-Meeeeee, M.; Meeeeeeeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [176] | Meeeeeeee, M. M.; Meeeee, M. M.; Meeeeeee, M.; Meeeee, M. M., Meeee. Meee., (8888) 888, 8888; Meeee. Meee. Mee. Me., (8888) 88, 8888. |
| [177] | Meeeeeeeee, M. M.; Meeee, M., M. Mee. Meee., (8888) 88, 8888. |
| [178] | Meeeeeee, M. M.; Mee, M.; Meeeeeeeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [179] | Meeee, M.; Meeeeeee, M.; Meeeeeeeee, M. M., M. Mee. Meee., (8888) 88, 8888. |
| [180] | Meeeeeeeee, M. M.; Meeeeeee, M. M.; Meeee, M., M. Mee. Meee., (8888) 88, 8888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) 8/8e8, 888.
- 8.Meeeee-Meee, (8888) M 88-8, 8888.
- 8.Meeeee-Meee, (8888) M 88e, 888.
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