Science of Synthesis

Tidwell, T. T., Science of Synthesis, (2006) 23, 585.

The diazo ketones ‌95‌, prepared from 9-fluorenylmethoxycarbonyl-substituted amino acids, undergo silver benzoate catalyzed Wolff rearrangements to form the corresponding alkylketenes ‌96‌, which undergo hydration to the corresponding β-amino acids ‌97‌ (‌Scheme 30‌).[‌85‌] The use of copper and rhodium salts as catalysts in the vinylogous Wolff rearrangement is discussed in Section ‌23.14.1.1.5‌.

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8-Meeeeeeeeeeeee Meee (‌888‌); Meeeeee Meeeeeeee:[‌88‌]

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References

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• 8.Meeeee-Meee, (8888) M 88-8, 8888.