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24.2.10.1.4 Method 4: Reaction of Esters of Phosphinous, Phosphonous, and Phosphorous Acids (Michaelis–Arbuzov and Related Reactions)

DOI: 10.1055/sos-SD-024-00466

Heydt, H.Science of Synthesis, (200624448.

The MichaelisArbuzov and MichaelisBecker reactions are standard protocols for the synthesis of acylphosphine oxides, acylphosphinates, and acylphosphonates. Further information may be found in HoubenWeyl, Vols. 12/1, 12/2, E 1, and E 2. The related Perkow reaction involves the synthesis of [1-(organooxy)alk-1-enyl]phosphonates from α-haloketones.[‌39‌]

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