Navigation

0 Hits

  • Previous / Next

You are using Science Of Synthesis as a Guest.
Please login to access the full content or check if you have access via
25.1.2.6 Method 6: Oxidation at the Terminal Carbon Atom of an Alk-1-ene

DOI: 10.1055/sos-SD-025-00010

Podlech, J.Science of Synthesis, (20072549.

The preparation of aldehydes from alkenes is possible by the formal anti-Markovnikov addition of water and the subsequent oxidation of the adducts. Typically, hydroboration followed by stronger oxidation conditions than sodium hydroxide/hydrogen peroxide treatment (which would give an alcohol) is the method of choice. Other oxidative procedures, especially Wacker oxidations, are successful in very special cases.


Cookie-Einstellungen