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25.1.12.2.1 Variation 1: Using Hydrogen and a Platinum Catalyst

DOI: 10.1055/sos-SD-025-00209

Hashmi, A. S. K.Science of Synthesis, (200725326.

Iodoalkanes 37 can undergo direct reductive carbonylation to form aldehydes 38 (Scheme 9).[‌112‌,‌113‌] Even the presence of β-hydrogen atoms is no problem, because β-hydride elimination does not occur. An indirect proof of this is the fact that neither C=C bonds in substrates nor normal alkenes undergo hydroformylation; so there is no pathway for β-hydride elimination and subsequent hydroformylation.

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