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25.2.1 Product Subclass 1: 2-Oxoaldehydes

DOI: 10.1055/sos-SD-025-00278

Olpp, T.Science of Synthesis, (200725423.

For the synthesis of 2-oxoaldehydes (glyoxals) several efficient methods have been developed, in the majority of cases based on oxidative reactions. Depending on the method and the substitution, glyoxals can be obtained either as a dioxo form 1, hydrated forms, such as hydrate 3, hemihydrate 2,[‌1‌,‌7‌] or bishydrate 4,[‌8‌] as enol forms 5, as oligomers,[‌8‌] or mixtures thereof (Scheme 1).

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