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26.1.1.2.2.4 Variation 4: With Chromic Acid in a Two-Phase System

DOI: 10.1055/sos-SD-026-00003

von Angerer, S.Science of Synthesis, (20052647.

The oxidation of alcohols with chromic acid can also be performed in a two-phase system with either diethyl ether or benzene as the organic solvent.[‌77‌] By this modification other structures that are sensitive to oxidation or acid-catalyzed hydrolysis remain intact. A variety of vinyl, e.g. 24,[‌78‌] and cyclic ketones, e.g. 25,[‌79‌] are prepared according to this method (Scheme 16).

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