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Please login to access the full content or check if you have access via Variation 5: With Chromium(VI) Oxide in Pyridine

DOI: 10.1055/sos-SD-026-00003

von Angerer, S.Science of Synthesis, (20052649.

An alternative to the Jones reagent is the Sarett reagent[‌80‌] which consists of a 1:2 complex of chromium(VI) oxide and pyridine. It is prepared by careful addition of chromium(VI) oxide to pyridine. (Note: The reverse addition leads to spontaneous ignition of the mixture.) It is a mild oxidizing agent[‌81‌] that is particularly useful for the preparation of ­steroids with acid-sensitive groups.[‌80‌] A variety of partially protected glucosides have been selectively oxidized with this reagent.[‌7‌,‌82‌]

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