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DOI: 10.1055/sos-SD-026-00142

Figadère, B.; Franck, X.Science of Synthesis, (200526272.

Thioesters bearing S-alkyl, and S-aryl groups react with boronic acids to give excellent yields of the corresponding ketones. Unlike the case with SuzukiMiyaura couplings, the presence of a base is detrimental, so these reactions are conducted under base-free conditions. The coupling reactions proceed in the presence of a catalytic amount of tris(di­benzylideneacetone)dipalladium(0), tri-2-furylphosphine, and copper(I) thiophene-2-carboxylate (1.6 equiv) in tetrahydrofuran at 50°C to give ketones 48 (Scheme 45).[‌199‌]

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