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26.1.4.7 Method 7: Synthesis from Nitriles

DOI: 10.1055/sos-SD-026-00142

Figadère, B.; Franck, X.Science of Synthesis, (200526277.

Aryl Grignard reagents react with nitriles to give, after acidic hydrolysis, phenyl ketones in good yields,[‌233‌] but several other reagents such as organolithium, organozinc, organotitanium, or alkylidenephosphorane reagents can be used for this transformation.

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