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26.1.8.8 Method 8: Rearrangement of 1,2-Diheterofunctionalized Compounds

DOI: 10.1055/sos-SD-026-00328

Constantieux, T.; Rodriguez, J.Science of Synthesis, (200526440.

Since the pioneering work in 1860 concerning the sulfuric acid promoted transformation of pinacol to pinacolone,[‌201‌] the skeletal reorganization of 1,2-diol derivatives via migration of a substituent to form a ketone has been known as the pinacol[‌202‌] or semipinacol[‌203‌] rearrangement (Scheme 51), depending on the nature of the substrate and conditions.[‌202‌,‌203‌]

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References