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26.2.1.7 Method 7: Ring Formation by [2+2] Cycloaddition

DOI: 10.1055/sos-SD-026-00397

Salaün, J., Science of Synthesis, (2005) 26, 564.

The regio- and stereoselective [2+2] cycloaddition of ketenes to alkenes is the most common nonphotolytic method to form four-membered carbocycles (see Houben–Weyl, Vol. 4/4, p 174). Numerous reviews have been written on the synthetic usefulness of the resulting [2+2] cycloadducts.[‌6‌,‌27‌,‌35‌–‌40‌]

References

[6] Meeeee, M.; Meeee, M., Meeee. Meee., (8888) 888, 888; Meeee. Meee. Mee. Me. Meee., (8888) 88, 888.
[27] Meeee, M. M.; Meee, M. M.; Mee, M., Me.; Meeee, M. M., Me., M. Me. Meee. Mee., (8888) 88, 8888.
[35] Mee-Meee, M., Me Meeeeeee ee Meeeee ee Meeeeee Meeeeeeee, Meeeee, M., Me.; MMM: Meeeeeeee, MM, (8888); Mee. 8, ee 888–888.
[36] Meeeee, M. M., M. Meee. Meee., (8888) 88, 88.
[37] Meeee, M. M., Meeeeeeee, (8888), 888.
[38] Meeee, M. M., Me Mee Meeeeeeee ee Meeeeee, Meeeeee eee Meeeeee Meeeeeeee, Meeee, M., Me.; Meeee: Mee Meee, (8888); e 888.
[39] Meeeee, M. M., Meee. Mee., (8888) 88, 888.
[40] Meeeee, M.; M'Meeeeee, M. M., Me Meeeeeeeee Meeeeeeee, Meeeeeee, M. M.; Meee, M. M., Mee.; Meeeeeee: Mee Meee, (8888); Mee. MMM, e 88.

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  • 8.Meeeee-Meee, (8888) M 88-8, 888.
  • 8.Meeeee-Meee, (8888) M 88-8, 8888.
  • 8.Meeeee-Meee, (8888) M 88-8, 8888.
  • 8.Meeeee-Meee, (8888) M 88-8, 8888.
  • 8.Meeeee-Meee, (8888) M 88-8, 8888.
  • 8.Meeeee-Meee, (8888) M 88-8, 8888.
  • 8.Meeeee-Meee, (8888) M 88e, 8888.
  • 8.Meeeee-Meee, (8888) M 88e, 888.
  • 8.Meeeee-Meee, (8888) M 88e, 888.
  • 8.Meeeee-Meee, (8888) M 88e, 888.

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