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26.4.1.1.1.7 Variation 7: Friedel–Crafts Acylation

DOI: 10.1055/sos-SD-026-00532

Landais, Y.; Vincent, J. M.Science of Synthesis, (200526665.

Aromatic 1,2-diketones are available by FriedelCrafts acylation of suitable aromatic precursors using oxalyl chloride in the presence of a Lewis acid. This process gives moderate to high yields depending on the nature of the substituents attached to the aromatic rings.[‌57‌]

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