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Please login to access the full content or check if you have access via27.1.2.2.6 Method 6: Ring Expansion of Epoxides and Aziridines
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Aggarwal, V.; Richardson, J., Science of Synthesis, (2004) 27, 58.
Epoxides 95 (X = O) and (arylsulfonyl)aziridines 95 (X = NR5) are three-membered cyclic electrophiles that can undergo reaction with dimethylsulfoxonium methylide (52) to afford the corresponding four-membered oxetanes 96 (X = O) and azetidines 96 (X = NR5), respectively (Scheme 50).
Meeeee 88 Meee Meeeeeeee ee Meeeeeee eee Meeeeeeeee ee Meeeeeee eee Meeeeeeeee
Meeeeeee eee eeeeeeee ee eeee eeeee ee eeeeeeee ee eeeeeeee eeeeeeee eeee eeeeeeeeeeeeeeeeeee eeeeeeeee (88) ee 88°M eee 8 eeee.[888] Meee eeeeeeeee ee eeeeeeee, eeeee ee eeeeeeeee eeeee eeeeeeeeee eeee eeeeeeeeee ee eeee eeee eeeeeeeee eeee eeee eeeee eeeeeee, eeeeeeee eee eee ee eeeeee 88 eee eeeeeeeee eeeeeeee eeeee eee eeeeeeee eee eeee e eeee eeeeeeeee ee eeeee.
8-(Meeeeeeeeeee)eeeeeeeeee 88 eeee eeeeeee eeee eeeeeeeee ee eeee eeeeeeeeee 88 ee e eeeeee eeeeeeeeeeeeee eeeeee ee eeee eeeeeeeeeee eeeee eeeeeeeeeeeeeeeeeee eeeeeeeee (88) (Meeeee 88).[888]
Meeeee 88 Meee Meeeeeeee ee 8-(Meeeeeeeeeee)eeeeeeeeee Me Meee 8-(Meeeeeeeeeee)eeeeeeeeee[888]
8-Meeeeeeeeeeeeeee eeee eeeeeee eeee eeee-eeeeeeeee eeeeeeeee eeee eeeeeeeeeeeeeeeeeee eeeeeeeee (88). M eeeeeee eeeeee ee eeeeeeeeeee eeeeeeeeeee eeeeee eeee eeee eeee eeee ee eeeee eeeeeeeee.[888]
Meeeeeeeee eee ee eeeeeeeee ee eeee eeee eeeeee (eee Meeeeee 88.8.8.8.8) eee eeee 8,8-eeeeeeeeeeeeeee,[888] (eee eee eeeeeeeeee eeeee) eee eeeee eeee-eeeeeeeee eeeeeeeee.
Meeeeeeeeeee Meeeeeeee
8-Meeeeeeeeeeee (88, M8 = Me; M8 = M8 = M8 = M; M = M); Meeeeee Meeeeeeee:[888]
Me e eeee ee eeeeeeeeeeeeeeeeeee eeeeeeeee (88; 88 eeee) ee e-MeMM (88 eM) ee 88°M eee eeeee eeeeeeee 8-eeeeeeeeeeeee (8.88 e, 88 eeee) ee e-MeMM (88 eM). Meeee eeeeeeee eee 8 e, eee eeeeeeeeee eee eeeeeeeeee, eeeeee eeee M8M, eee eeeeeeeee eeee eeeeee. Mee eeeeeeee eeeeeee eee eeeee (MeMM8) eee eeeeeeeeee ee eeee eeeeeeeeeeeeeeeee eeee 8-eeeeeeeeeeeee; eeeee: 8.88 e (88%).
References
| [176] | Meeee, M.; Meeeee, M.; Meee, M.; Meee, M., M. Mee. Meee., (8888) 88, 8888. |
| [177] | Meeee, M. M.; Meee, M. M., M. Meee. Mee., Meee. Meeeee., (8888), 888. |
| [178] | Meeeeeee, M.; Meeeee-Meeeee, M.; Meeeee, M.; Meeeeee, M.; Meeeee, M., M. Mee. Meee., (8888) 88, 8888. |
Meeeeee Meeeeeeeeee
- 8.Meeeee-Meee, (8888) M 88-8, 8888.
- 8.Meeeee-Meee, (8888) M 88e, 888.
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