0 Hits

  • Previous / Next

You are using Science Of Synthesis as a Guest.
Please login to access the full content or check if you have access via Method 1: By Deprotonation of Sulfonium Salts

DOI: 10.1055/sos-SD-027-00002

Aggarwal, V.; Richardson, J.Science of Synthesis, (20042759.

As conjugate bases of the corresponding sulfonium salts, the most commonly employed method for the synthesis of sulfonium ylides 99 is deprotonation (Scheme 52). The popularity of deprotonation as a method for the generation of sulfonium ylides can be ascribed to the ease with which sulfonium salts can be prepared. The experimental conditions used for deprotonation vary widely according to the intended use, stability of the ylide, and the pKa of the sulfonium salt.

Meeeee 88 Meeeeeeee ee Meeeeeeee Meeeee ee Meeeeeeeeeeee

Me eeeeeeeee, eee eeeeeeeee eeee eeeeeeee ee eeeee eee α-eeeeeeee eeee eee ee eeeeeeeee eeee ee eeeee. Meeeeee, ee eeeeeeee, eeee eeeeee ee eeee eeeeeeeeee ee eeeee eeeeeeeeee eeeeeeeeee. Meeeeee, eeee eee eeeee ee eee eeeeee eeeeeeee ee eeeeee eee eeeeeeeee, ee ee eeeeeeeeeeeeeee eeeee α-eeeeeeee ee eeeeeeeeee. Meeeeeeeeeeee ee eeee eeeeeeeeee ee eeeee eeeee eeeee eee ee eee ee eee eeeeeeeeeeee eeee ee α-eeeeeeeee, eee eeeee eeee ee eee eeeeeeeee. Mee eeee eeeee eeeeeeeeee eeeeeeeee ee eeeee eeee eeeeee ee eeeeeeeeee eeeeeeeeeeee eeeee eeeee ee eeeeeeeeeee eeeeeeeeee ee eee eeeeeee ee eee eeeeeee eeeeeeeee α-eeeeeeeee. Meee, eeeeeeeeee eee eeee-eeeeeeeeee eeeeee eee ee eeeeeeeeeee ee eee eeeeeeee ee e eeeeeee ee eeeeeeeee α-eeeeeeee eeeee. Meeeeee, eee eeeeeeeee ee eeee ee eeee eeeeeeeeeeeee eeeeee (e.e., eeeee eeeeeee eeeeee eeee ee eee eeeeeeeee, ee eeee eeeeeeeeeee eeeeeeee eeeeee) eeeeee ee eeeeeeee ee eee eeeeeeee ee eeee eeeeee eeeeeee. Meee eeeeeeeeeeee eee eeeeeeeeeee ee eee eeeeeeeeeee ee eeeeeeeeeeeeeeeee eeeeeeeeeeee (eee Meeeeee[‌888‌]

Mee eeee ee eeeeeeeeeeeee ee e eeeeeeeee eee eee eee eeeeeeeee ee eee eeeeeeeee eeeee eeee eeeeeeee eeee eee eeeeee ee eee eeeeeeeeeeee eeeeeeee ee eee α-eeeeee. Me eeeee eeeeeeeeeeee eee eeeeeeee-eeeeeeeeeee, eeeeeeeeeeeee eeeeeeee eeee e eeee eeee eeee. Meeeeee, ee eeeee eee ee eeeeeeeeeeee, e eeeeee eeee, eeee ee eeeeeeeee eeee-eeeeeeee ee eeeeee eeeeeee ee eeeeeeee eeeeeeeee ee eeeeeeee eee eee eeeee eeeeeee eeeeeeeee eeeeeeee, eeeeeeeeeeeee eeeeeee ee eeeeeeeeeeee eeeee 8°M. Meeeeeeee e-eeeeeeeee eeeeeee eeee eee eeeee eeeeeeeeeee eee eeeeeee eeeeeeeeeeee eee eee ee eeeeeeeeeeeeee eeeeeeee ee 88°M ee eeeeeeeeeeeeeee eeeeeeee eeeee eeeeee eeeeeeeeeeee, eeeeee eeeee eeee ee eeee-eeeeeeeeeeee ee eeeeeee eeeeeeeeeeeeeeee. Meee eeee eeeeeeeeeeee ee eee eeeeeee eeeeee eee eeeee eeeeee, eeeeeeeeeeeee ee eee eeeeeeeee eeee eeeeeeeee eeeeeee eeeeeeeeeeee eeeeeeeee (eee Meeeeee